口腔疾病防治 ›› 2021, Vol. 29 ›› Issue (8): 572-576.doi: 10.12016/j.issn.2096-1456.2021.08.012

• 综述 • 上一篇    

急性淋巴细胞白血病患儿的口腔健康管理

唐雅文1(),张琳1,杨雪2,邹静3,王艳3()   

  1. 1.口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院,四川 成都(610041)
    2.四川大学华西第二医院儿科,四川 成都(610041)
    3.口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院儿童口腔科,四川 成都(610041)
  • 收稿日期:2020-10-26 修回日期:2021-02-28 出版日期:2021-08-20 发布日期:2021-05-13
  • 通讯作者: 王艳 E-mail:2821986848@qq.com;wangyan1458@scu.edu.cn
  • 作者简介:唐雅文,本科,Email:2821986848@qq.com
  • 基金资助:
    国家自然科学基金项目(81600864)

Oral health management in children with acute lymphoblastic leukemia

TANG Yawen1(),ZHANG Lin1,YANG Xue2,ZOU Jing3,WANG Yan3()   

  1. 1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
    2. Department of Pediatric, West China Second University Hospital, Sichuan University, Chengdu 610041, China
    3. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2020-10-26 Revised:2021-02-28 Online:2021-08-20 Published:2021-05-13
  • Contact: Yan WANG E-mail:2821986848@qq.com;wangyan1458@scu.edu.cn
  • Supported by:
    National Natural Science Foundation of China(81600864)

摘要:

急性淋巴细胞白血病是儿童最常见的白血病类型。近年来急性淋巴细胞白血病患儿的治疗和预后已有显著的提高,但该病及其治疗措施可导致多种口腔并发症,影响进一步治疗,对患儿影响大,不利于疾病的控制。为提高患儿生存质量,本文围绕急性淋巴细胞白血病患儿口腔健康状况及口腔健康管理作一综述,为临床提供参考。文献回顾表明,针对急性淋巴细胞白血病患儿的口腔健康管理措施主要包括:做好口腔健康教育;肿瘤治疗开始前及时治疗口腔疾病,消除潜在感染源,但应注意对患儿进行血液检查并评估风险;治疗期间针对患儿口腔黏膜问题对症处理;治疗期间如出现口腔急症,应在血液科医生指导下进行处理;定期进行口腔检查及护理。目前仍缺乏针对口腔黏膜炎的有效防治措施,口腔黏膜炎作为急性淋巴细胞白血病患儿常见口腔疾病,其预防及治疗仍有待进一步研究。

关键词: 急性淋巴细胞白血病; 儿童白血病; 化疗; 并发症; 儿童口腔; 口腔护理; 口腔病变; 口腔感染; 口腔健康管理

Abstract:

Acute lymphoblastic leukemia is the most common type of leukemia in children. In recent years, the treatment and prognosis of acute lymphoblastic leukemia in children have improved significantly. However, acute lymphoblastic leukemia itself and treatment measures can lead to a variety of adverse oral complications and affect further treatment. These complications have a significant effect on patients and affect further treatment. To improve the quality of life of children, this article reviews the oral health status and oral health management of children with acute lymphoblastic leukemia for clinical reference. The literature review shows that the oral health management measures for children with acute lymphoblastic leukemia mainly include oral health education, active prevention of oral diseases, timely oral treatment before the start of antitumor treatment, elimination of potential sources of infection after blood examination and risk assessment, treatment of oral mucosal problems during therapy, oral emergency during antitumor therapy should be carried out under the guidance of hematologists and regular oral inspection and oral care. However, current studies have found that there is still a lack of effective prevention and treatment measures for oral mucositis. As a common oral disease in children with acute lymphoblastic leukemia, the prevention and treatment of oral mucositis remain to be further studied.

Key words: acute lymphoblastic leukemia; pediatric leukemia; chemotherapy; complications; pediatric dentistry; oral care; oral lesions; oral infection; oral health management

中图分类号: 

  • R78