Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (4): 236-240.doi: 10.12016/j.issn.2096-1456.2019.04.006

• Cinical Study • Previous Articles     Next Articles

Study on the correlation between common diseases of oral mucosa and psychological factors

LIN Lin,DUAN Ning,WANG Xiang,SONG Yuefeng,WANG Wenmei()   

  1. Department of oral mucosa disease, Nanjing Stomatological Hospital, Medical School of Nanjing University, Jiangsu Nanjing 210008, China.
  • Received:2018-11-19 Revised:2019-01-04 Online:2019-04-20 Published:2019-04-28
  • Contact: Wenmei WANG E-mail:wangwenmei0102@163.com

Abstract:

Objective To explore the relationship between psychological factors and recurrent aphthous ulcer (RAU), oral lichen planus (OLP), and burning mouth syndrome (BMS) and to provide a reference for clinical diagnosis and treatment of the disease.Methods From July to October 2018, 50 patients with common RAU, refractory RAU, OLP and BMS were selected as the observation group, and 50 healthy participants without major systemic diseases and oral mucosal diseases matched for age and sex served as the control group. The psychological status of the subjects in each group was investigated by questionnaires, including the generalized anxiety disorder 7-item scale(GAD-7) and the patient health questionnaire-9 (PHQ-9).Results Compared with the control group, the PHQ-9 scores in the refractory RAU, common RAU, OLP and BMS groups were higher than those in the control group (P < 0.05), and the GAD-7 scores in the refractory RAU, OLP and BMS groups were higher than those in the control group (P < 0.05). In the RAU group, the GAD-7 score of intractable RAU was higher than that of common RAU (P < 0.05), and there was no significant difference in the PHQ-9 score (P > 0.05).Conclusion RAU, OLP and BMS are common psychosomatic diseases presented by patients in the Department of Oral Mucosal Diseases. Their occurrence and development are related to the psychological status of patients. A tendency toward anxiety is significantly more common among refractory RAU patients than common RAU patients.

Key words: Oral mucosa, Recurrent aphthous ulcer, Oral lichen planus, Burning?mouth?syndrome, Psychological factors, Anxiety, Depression

CLC Number: 

  • R781.5

Table 1

Comparison of GAD-7 and PHQ-9 scores between the RAU/OLP/BMS groups and the control group n=50,$\bar{x}$± s"

组别 GAD-7 PHQ-9
$\bar{x}$± s t P $\bar{x}$± s t P
普通性RAU 1.56±1.63 2.359 0.061 1.74±1.74 4.597 < 0.001
顽固性RAU 2.76±2.15 5.369 < 0.001 2.36±2.38 5.281 < 0.001
OLP 2.34±1.85 4.660 0.004 1.52±1.63 4.020 0.002
BMS 3.48±2.23 7.219 < 0.001 3.26±2.36 7.804 < 0.001
对照组 0.88±1.12 0.44±0.98
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