婚姻状态对颊黏膜鳞癌患者生存的影响
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秦玲玲,陈莺,苏淼,张汉斌
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Prognostic impacts of marital status on patients with buccal mucosa squamous cell carcinoma
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QIN Lingling,CHEN Ying,SU Miao,ZHANG Hanbin
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Table 2 Univariate and multivariate analyses of prognostic factors in patients with buccal squamous cell carcinoma
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Variables | Univariate analysis | Multivariate analysis | HR (95% CI) | P | HR (95% CI) | P | Marital status | | < 0.001 | | 0.001 | Married | 1 | | 1 | | Never married | 1.439(1.137-1.822) | 0.003 | 1.297(1.012-1.661) | 0.040 | Unhappily married | 1.751(1.439-2.132) | < 0.001 | 1.445(1.173-1.780) | 0.001 | Age at diagnosis | | < 0.001 | | < 0.001 | ≤ 60 years | 1 | | 1 | | >60 years | 1.634(1.347-1.983) | < 0.001 | 1.640(1.330-2.023) | < 0.001 | Sex | | 0.011 | | 0.908 | Male | 1 | | 1 | | Female | 1.251(1.052-1.489) | 0.011 | 1.011(0.839-1.218) | | Race | | 0.081 | – | | White | 1 | | | | Black | 1.223(0896-1.669) | 0.206 | | | Others* | 0.799(0.616-1.036) | 0.091 | | | Year of diagnosis | | 0.218 | – | | 2004-2009 | 1 | | | | 2010-2015 | 0.893(0.747-1.069) | 0.218 | | | Grade | | < 0.001 | | 0.017 | Hight | 1 | | 1 | | Low | 1.563(1.266-1.929) | < 0.001 | 1.302(1.049-1.615) | 0.017 | AJCC stage | | < 0.001 | | < 0.001 | Ⅰ | 1 | | 1 | | Ⅱ | 1.312(0.961-1.790) | 0.087 | 1.152(0.843-1.574) | 0.374 | Ⅲ | 2.023(1.488-2.750) | < 0.001 | 1.713(1.255-2.338) | 0.001 | Ⅳ | 4.100(3.165-5.310) | < 0.001 | 3.281(2.507-4.294) | < 0.001 | Surgery | | < 0.001 | | < 0.001 | No evidence | 1 | | 1 | | Yes | 0.223(0.183-0.271) | < 0.001 | 0.331(0.270-0.407) | < 0.001 |
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