口腔疾病防治 ›› 2019, Vol. 27 ›› Issue (6): 391-395.DOI: 10.12016/j.issn.2096-1456.2019.06.010

• 综述 • 上一篇    下一篇

氟牙症影响因素的研究进展

邓佳欣,陈媛,付琢惠,王艳()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床研究中心 四川大学华西口腔医院儿童口腔科,四川 成都(610041)
  • 收稿日期:2018-05-29 修回日期:2018-08-07 出版日期:2019-06-20 发布日期:2019-06-21
  • 通讯作者: 王艳
  • 作者简介:邓佳欣,学士,Email: 291986594@qq.com
  • 基金资助:
    国家自然科学基金项目(81600864);四川大学青年教师科研启动基金项目(2017SCU11007)

Research progress on the influencing factors of dental fluorosis

Jiaxin DENG,Yuan CHEN,Zhuohui FU,Yan WANG()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Pediatric Dentistry West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-05-29 Revised:2018-08-07 Online:2019-06-20 Published:2019-06-21
  • Contact: Yan WANG

摘要:

氟牙症是在牙齿发育过程中因摄氟过量导致牙釉质中矿物质含量降低和孔隙率增加,从而引起的一种牙釉质发育不全,可影响牙齿功能和患者的美观。氟牙症在全球范围内的患病率居高不下,其发生受多方面因素的影响。其中,过量的氟摄入是氟牙症发生的主要危险因素。氟的摄入途径主要包括氟化物的应用、日常饮食和空气。近几十年来由于氟化物广泛应用于预防龋病,且氟暴露途径不断增加,越来越多的研究对氟化物如何在有效防龋和预防氟牙症之间取得平衡进行探索。此外,较早年龄的氟暴露也可增加氟牙症发生风险,而营养结构的改善可对氟牙症起预防作用,基因易感性、社会经济地位及家长意识均可对氟牙症的发生产生一定影响。本文就氟牙症影响因素的最新研究进展进行综述,为氟牙症的防治提供参考。

关键词: 氟牙症, 氟化物, 营养因素, 年龄, 基因易感性

Abstract:

Dental fluorosis is a kind of enamel hypoplasia caused by excessive fluorine intake during tooth development, leading to the formation of enamel with a lower mineral content and increased porosity, which can affect dental function and patients′ appearance. The prevalence of dental fluorosis remains high on a global level, and its occurrence is affected by many factors. Excessive fluorine intake is a major risk factor for dental fluorosis. The ways of fluorine intake mainly includes the application of fluorides, daily diet and air. Since fluorides have been widely used in the prevention of caries in recent decades and the methods of exposure to fluorine have been increasing, increasing numbers of studies have been conducted to explore how fluoride can achieve a balance between the effective prevention of caries and the prevention of dental fluorosis. In addition, exposure to fluorine at earlier ages can also increase the risk of dental fluorosis, while the improvement of nutritional structure can affect dental fluorosis prevention. Genetic susceptibility, socioeconomic status and parental awareness may influence dental fluorosis. This article aimed to review the latest research progress on the factors influencing dental fluorosis and provide a reference for the prevention and treatment of dental fluorosis.

Key words: Dental fluorosis, Fluoride, Nutrition factors, Age, Genetic susceptibility

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