正畸牙移动困难相关因素研究进展
口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院正畸科,四川成都(610041)
Research progress on factors related to the difficulty of orthodontic tooth movement
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
通讯作者: 刘钧,教授,博士,Email:junliu@scu.edu.cnTel:86-28-85502207
责任编辑: 罗燕鸿
收稿日期: 2020-10-16 修回日期: 2020-12-12 网络出版日期: 2021-05-20
| 基金资助: |
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Corresponding authors: LIU Jun, Email:junliu@scu.edu.cn, Tel: 86-28-85502207
Received: 2020-10-16 Revised: 2020-12-12 Online: 2021-05-20
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作者简介 About authors
孟庆琰,住院医师,硕士,Email:496272019@QQ.com
正畸牙移动是以牙周组织塑建为生物学基础的复杂生理过程。许多因素如口颌复合体的解剖特征、咬合干扰、机械因素及系统性因素等都可能对其造成影响,导致正畸牙移动困难。近年来,国内外学者非常关注牙移动困难相关因素的研究,但当前有关正畸牙移动困难的研究多为动物实验及回顾性研究,亟需高质量的临床试验及循证医学研究。许多正畸牙移动困难相关因素的作用机制尚存在争议,未形成一个普遍认可的完善理论体系,目前认为牙槽骨缺损、上颌窦、牙龈、牙根粘连、骨岛和摩擦力等因素都可能导致正畸牙移动困难。了解正畸牙移动困难的相关因素有助于正畸医生为患者制定更全面的个性化治疗方案,实现更高效、安全的牙移动。本文对目前正畸牙移动困难的相关因素作一综述,为正畸临床治疗提供参考。
关键词:
Orthodontic tooth movement is a complex physiological process based on periodontal tissue remodeling. Numerous factors, such as the anatomical characteristics of oral and maxillofacial complications, occlusal interference, mechanical factors and systematic factors, may play critical roles in orthodontic tooth movement, leading to tooth movement difficulty. In recent years, many scholars have focused on factors related to tooth movement difficulty, but current research mostly involves animal experiments and retrospective studies. Clinical trials of high-quality and evidence-based medicine studies are required. Although no sound theory system is available that is universally recognized and the mechanism of many factors remains debatable, alveolar bone defects, the maxillary sinus, the gingiva, tooth ankylosis, bone islands and friction may cause orthodontic tooth movement. Understanding the factors related to the difficulty of orthodontic tooth movement is advantageous to develop a more comprehensive personalized treatment plan for patients and achieve more efficient and safer tooth movement. In this paper, the current factors related to orthodontic tooth movement are reviewed to provide references for clinical orthodontic treatment.
Keywords:
本文引用格式
孟庆琰, 刘钧.
MENG Qingyan, LIU Jun.

开放科学(资源服务)标识码(OSID)
正畸牙移动被定义为牙颌复合体的生理平衡受外力干预后的生物反应的结果[1]。其生物学基础是牙周组织的塑建,包括骨组织的可塑性、牙骨质的抗压性和牙周膜内环境的稳定性等。传统的正畸疗程一般为2~3年,长时间的正畸治疗是龋齿[2]、黏膜疾病[3]和牙根吸收[4]等并发症的潜在危险因素。充分了解正畸牙移动困难的相关因素可帮助正畸医生从正畸材料学、生物学、生物力学和解剖学等不同角度完善正畸治疗方案,提高牙移动效率,缩短疗程,减少正畸副作用及并发症的发生。当前牙移动困难相关因素的研究多为回顾性研究和动物实验,缺乏可靠的随机对照临床试验和循证医学证据,且许多影响因素的作用机制仍处于争议中,尚未形成一个普遍认可的完善理论体系。本文旨在对目前正畸牙移动困难的相关因素作一综述,为正畸临床治疗提供参考,以期实现更高效、更安全的牙移动。
1 牙槽骨缺损或骨皮质阻碍
牙槽骨缺损是指牙槽骨结构的不完整,包括三维方向上牙槽骨结构的不连续,主要表现为骨开窗及骨开裂。骨开窗是指牙槽嵴顶完整,牙唇(颊)、舌(腭)侧牙槽骨缺损形成的裂隙,牙根暴露于牙槽骨外,牙根表面仅有骨膜和牙龈附着。骨开裂指牙根唇颊侧或舌腭侧牙槽嵴边缘的V形骨缺损,自牙槽嵴顶向根方延伸[5]。除了先天存在的牙槽骨缺损,正畸治疗过程中牙齿移动的方向、正畸力的大小和频率、解剖的特异性等都可能影响牙槽骨缺损的发生发展。
正畸生物力学设计会增大骨开窗和骨开裂发生的可能性,而骨开裂与骨开窗会严重影响牙移动速率。正畸治疗应尽量避免牙移动途径超过牙槽骨边界,确保牙齿在移动过程中不与骨皮质接触以降低牙槽骨缺损风险。前牙区牙槽骨板较薄,转矩的改变更易引起骨开窗或骨开裂。上颌扩弓可能会使后牙颊倾,减小后牙颊侧骨板厚度,更易导致骨开裂或骨开窗,特别是快速上颌扩弓(rapid maxillary expansion,RME)所加力值较大,加剧牙槽骨缺损的倾向[10]。Lo Giudice等[11]研究发现RME会显著降低牙槽骨颊侧骨板厚度,建议对于颊侧骨板较薄的患者慎重选择快速扩弓。对于正颌手术前去代偿的患者,骨皮质切开术辅助正畸治疗可以保护上下前牙,有效改善前牙骨开窗与骨开裂[12]。
锥形束CT在三维方向上对牙槽骨骨量及形态的测量有助于骨开裂、骨开窗的诊断[13]。正畸治疗前应拍摄锥形束CT了解患者牙槽骨三维方向上的形态特征以及是否存在骨开窗骨开裂的危险因素,根据牙槽骨形态采取合理的正畸生物力学设计和矫治策略,保持牙移动和颌骨改建的平衡,预防牙槽骨缺损。
小于3 mm的骨开窗与骨开裂,可依靠骨组织的修复能力自愈[14]。当牙槽骨缺损较大、机体自我修复能力无法代偿时,可采取骨再生技术干预。目前临床上常用的骨组织再生技术主要包括骨皮质切开术伴骨移植和引导骨再生技术(guided bone regeneration, GBR)。骨皮质切开术辅助自体或异体骨移植可有效增加骨量,扩大牙齿移动范围,避免牙槽骨缺损。Ahn等[15]研究结果也表明该方法用于预防前牙去代偿过程中可能出现的骨开裂和骨开窗是安全可行的。GBR技术多选择颗粒填料和含有不同细胞因子的生物膜促进组织修复,安全性和有效性得到了广泛认同。目前GBR在修复牙槽骨缺损方面的研究由于样本量限制、随机对照试验的缺乏,关于哪种膜材料和手术方法对修复牙槽骨缺损更安全高效仍有较大争议[16]。近年来组织工程技术迅速发展,为牙槽骨缺损的修复开辟了新的途径,但骨组织工程技术修复牙槽骨缺损的研究目前仍处于实验室阶段,临床应用较少。
2 经上颌窦的牙移动
经上颌窦的后牙间隙关闭是正畸治疗中的常见难题,在临床治疗过程中往往遇到许多困难,因为通过上颌窦的牙移动是有限度的。上颌窦底对于拔牙间隙关闭的影响主要表现在前磨牙区和磨牙区。上颌窦底垂直向延伸过多时,可能干扰上颌后牙的移动轨迹,导致该区域牙齿移动困难,牙根吸收风险增大,上颌后牙过度萌出和上颌后牙的拔除都可能会引起上颌窦向下扩张,发生上颌窦气化,影响上颌后牙区拔牙间隙的关闭[19]。虽然在临床中实现经上颌窦的牙齿移动颇为困难,但并非无法实现。Cha等[20]通过持续轻力的应用和牙齿的低速移动,成功实现了经上颌窦的牙移动,有效改善了面部或唇部凸度,实现了良好的咬合关系和牙根平行度,且未见明显牙根和牙槽骨吸收。
经上颌窦的正畸牙移动研究很多,且观点不一。目前普遍认可的观点为上颌窦会影响正畸拔牙间隙的关闭,集中表现在上颌后牙区。经上颌窦的牙齿移动是可以实现的,但正畸医生需要充分了解患者上颌窦及其毗邻的解剖结构特征,设计合理的力学体系,通过持续轻力实现牙齿的低速移动,合理控制力与力矩的比值和应力分布,并在治疗过程中根据患者的实际情况不断调整治疗策略,以实现安全、高效的正畸治疗。正畸医生对经上颌窦的牙移动仍应持谨慎态度,因为目前可参考的研究多为病例报告,缺乏随机对照研究和强有力的循证医学证据。
3 牙根粘连
4 牙龈阻碍
一般情况下正畸治疗过程中牙龈组织的塑建较硬组织慢,变化较小,对正畸疗程、效果和稳定性影响也较小。但如果口腔卫生状况较差,牙菌斑堆积,可出现不同程度的牙龈肥大,牙龈增生严重者会覆盖牙面、矫治器或牙列间隙,影响牙齿移动,降低正畸治疗稳定性。牙龈肥大患者应首先行牙周基础治疗,术后部分患者牙龈肥大可自行消退。如牙周基础治疗效果欠佳,可根据情况行牙周外科手术切除多余的牙龈,手术方法包括传统手术刀切除、电刀切除或激光切除等[24]。
5 垂直骨面型、牙槽骨密度
6 邻牙、对颌牙干扰或咬合打开不足
7 骨岛
正畸过程中,当牙与硬度较高的组织(如致密骨皮质、骨岛)接触时,易导致牙根吸收和牙移动的失败。骨岛的实质是骨松质内的致密骨组织团块或结节,是一种非病理性变异,多发于下颌前磨牙根尖区。有病例报告显示[31],骨岛与牙移动冲突时,可能导致间隙关闭不全、牙齿的转矩及轴倾度难以控制和牙根吸收。针对存有骨岛的患者,应拍摄CBCT确定病变部位,根据牙齿移动量、移动方向与骨岛的关系,制定个性化正畸方案,以期实现安全和高效的正畸治疗。
8 机械因素
8.1 弓丝摩擦力
8.2 正畸力
正畸牙移动与治疗过程所加力值的大小、种类、作用时间等密切相关。正畸医生通过对牙齿施加一定矫治力并将应力传递到相应牙周组织,牙槽骨组织发生适应性骨塑建,产生牙齿的位移。最适正畸牙移动是通过持续轻力实现的,且牙齿移动患者不会出现明显不适和继发性病理性损伤[34]。从组织学水平上看,最适正畸力不应阻碍牙周组织正常血运循环,尽可能避免透明样变和牙槽骨潜行性吸收,同时促进生理性的成骨与破骨活动,实现牙齿移动。正畸力值过小无法实现牙齿移动,力值过大则会导致牙周膜透明样变和牙槽骨潜行性吸收,严重的会发生牙周膜坏死、牙根吸收、牙根与牙槽骨固着粘连,牙齿同样无法移动。
Ozkalayci 等[35]研究结果表明持续力的牙移动效率要明显高于间歇力,但相较于间歇力而言,持续力更易导致牙根吸收。牙周膜中分布的应力是组织改建的始动因素,决定细胞反应的类型和程度,从而决定牙移动的类型和速度,而牙倾斜移动过程中牙周膜应力分布不均,牙根和牙槽骨吸收风险较其他移动方式更高。
9 其他因素
综上所述,正畸牙移动是一个以牙周组织的塑建为生物学基础的复杂生理过程,解剖特征、机械因素、系统性因素等都可能导致牙移动的困难。国内外学者围绕正畸牙移动进行了广泛的研究,但是其具体的生物学和生物力学机制仍有许多问题亟待解决,需要全世界学者共同努力,以期形成一个关于正畸牙移动影响因素的统一理论体系。
【Author contributions】 Meng QY wrote the article. Liu J revised the article. All authors contributed to the article and approved the submitted version.

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Dehiscence and fenestration in patients with different vertical growth patterns assessed with cone-beam computed tomography
[J].OBJECTIVE: To test the null hypothesis that the presence of alveolar defects (dehiscence and fenestration) was not different among patients with different vertical growth patterns. MATERIALS AND METHODS: A total of 1872 teeth in 26 hyper-divergent (mean age: 24.4 +/- 4.8 years), 27 hypo-divergent (mean age: 25.1 +/- 4.5 years), and 25 normo-divergent (mean age: 23.6 +/- 4.1 years) patients with no previous orthodontic treatment were evaluated using cone-beam computed tomography. Axial and cross-sectional views were evaluated with regard to whether dehiscence and/or fenestration on buccal and lingual surfaces existed or not. For statistical analysis, the Pearson chi-square test was used at a P < .05 significance level. RESULTS: According to the statistical analysis, the hypo-divergent group (6.56%) had lower dehiscence prevalence than the hyper-divergent (8.35%) and normo-divergent (8.18%) groups (P = .004). Higher prevalences of dehiscence and fenestration were found on buccal sides in all vertical growth patterns. While fenestration was a common finding for the maxillary alveolar region, dehiscence was a common finding in the mandible in all groups. CONCLUSION: The null hypothesis was rejected. Although the prevalence of fenestrations was not different, significant differences for dehiscences were found in patients with different vertical growth patterns.
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[J].BACKGROUND: Correcting posterior crossbite in adult patients using nonsurgical methods may involve buccolingual tooth movement. Knowing the extent of the pretreatment alveolar bony dehiscences and fenestrations in the posterior area will aid orthodontists in planning posterior crossbite patients accordingly to minimize posttreatment bony defects. Before the advent of cone beam computed tomography (CBCT), observing buccal and lingual bony defects was not possible unless other treatment needs allowed for an open-flap procedure. With CBCT technology, we can now detect posterior defects with some accuracy. The aim of the present study was to determine the prevalence of posterior alveolar bony dehiscence and fenestration in adults with posterior crossbite compared with noncrossbite adults. METHODS: The study group consisted of pretreatment CBCTs of 28 samples with at least one or more teeth in posterior crossbite or edgebite. The comparison group consisted of pretreatment CBCTs of 28 samples with no posterior crossbite or edgebite. All buccal and lingual sides of the upper and lower posterior segments were measured for the presence of dehiscence, fenestration, and combined total bony defects. RESULTS: The prevalence of total bony defects was higher in the study group (61.6%) than in the comparison group (52.1%) (p < 0.05). While there was no difference in prevalence between crossbite teeth in the study group and noncrossbite teeth in the comparison group, the noncrossbite teeth in the study group showed a higher prevalence of total bony defects, dehiscence, and fenestration than the noncrossbite teeth in the comparison group (p < 0.05). The prevalence of dehiscence was higher in the study group (41.2%) than in the comparison group (33.3%) (p < 0.05). Neither the prevalence of fenestration nor the mean bony defect size showed statistical significance between the two groups. First premolars showed a higher prevalence of dehiscence than other posterior teeth, and maxillary posterior teeth had a higher prevalence of fenestration than mandibular posterior teeth. Among the maxillary posterior teeth, second premolars had the least amount of fenestration. CONCLUSIONS: Adult subjects with posterior crossbite had a higher prevalence of total bony defects and dehiscence, especially buccal dehiscence, in the posterior region than subjects with no posterior crossbite. This was due to the high prevalence observed in the noncrossbite teeth in posterior crossbite subjects.
Evaluation of dehiscence and fenestration in adolescents affected by bilateral cleft lip and palate using cone-beam computed tomography
[J].INTRODUCTION: We evaluated the dehiscence and fenestration presence in maxillary and mandibular anterior teeth of patients affected by bilateral cleft lip and palate (BCLP) and compared the findings with a well-matched control group of noncleft patients using cone-beam computed tomography. METHODS: Cone-beam computed tomography images of 51 patients were divided into 2 groups (group 1, 21 patients affected by BCLP; mean age; 14.62 +/- 2.89 years; and group 2, 30 patients as the noncleft control group; mean age, 14.22 +/- 1.05 years) and assessed them for dehiscence and fenestration in the anterior maxillary and mandibular teeth. Data were analyzed with the Student t test, Pearson chi-square test, and Fischer exact test. RESULTS: The prevalences of dehiscence in patients affected by BCLP were 61.11% in the maxillary and 48.41% in the mandibular anterior teeth, whereas the rates in the noncleft group were 7.78% and 16.67%, respectively (P < 0.001). The presence of fenestration was found to be statistically significantly higher in the maxillary central incisors of the BCLP group compared with the noncleft controls (P < 0.05), and almost similar rates were noted for the other teeth, with no statistically significant differences (P > 0.05). CONCLUSIONS: Our data suggest that patients affected by BCLP may have higher prevalences of dehiscence in the maxillary and mandibular anterior teeth and of fenestration in the maxillary central incisors.
Buccal bone plate thickness after rapid maxillary expansion in mixed and permanent dentitions
[J].INTRODUCTION: Rapid maxillary expansion (RME) might cause buccal displacement of anchor teeth. Dislocation of teeth outside their alveolar process can damage the periodontium; for this reason, maxillary expansion using deciduous teeth as anchorage in the mixed dentition might be suggested. The aim of this study was to compare changes of buccal bone plate thickness on the maxillary permanent first molars after RME in the mixed and permanent dentitions with different types of anchorage. METHODS: Two groups of patients were evaluated with cone-beam computed tomography before and after RME. Group E (21 patients) underwent RME using deciduous teeth as anchorage; group 6 (16 patients) underwent RME using permanent teeth as anchorage. The Wilcoxon test was used to compare changes between the time points in the same groups, and the Mann-Whitney U test was used to compare differences between the groups. RESULTS: In group E, generally, no statistically significant reduction was found in buccal bone plate thickness between the time points. In group 6, most measurements showed significant reductions in buccal bone plate thickness (P <0.05) between the time points, with a maximum decrease of 1.25 mm. CONCLUSIONS: RME in the mixed dentition with the appliance anchored to deciduous teeth did not reduce the buccal bone plate thickness of the maxillary permanent first molars, except for the mesial roots on both sides. RME in the permanent dentition caused a reduction of the buccal bone plate thickness of the maxillary permanent first molars when they were used as anchorage in the permanent dentition.
Alveolar bone changes after rapid maxillary expansion with tooth-born appliances: a systematic review
[J].
Changes of alveolar bone dehiscence and fenestration after augmented corticotomy-assisted orthodontic treatment: a CBCT evaluation
[J].BACKGROUND: To evaluate the changes of alveolar dehiscence and fenestration after augmented corticotomy-assisted orthodontic treatment on cone-beam computed tomography (CBCT) compared with traditional pre-surgical orthodontics, both quantitatively and qualitatively. METHODS: Two hundred and four anterior teeth from 17 skeletal class III malocclusions were divided into four groups. Groups G1 (upper teeth) and G3 (lower teeth), comprising 120 teeth, accepted traditional pre-surgical orthodontics; groups G2 (upper teeth) and G4(lower teeth), comprising 84 teeth, accepted augmented corticotomy-assisted pre-surgical orthodontics. The changes of alveolar bone dehiscence and fenestration of each tooth in all groups were evaluated with the help of CBCT. RESULTS: Quantitative analysis for comparing both groups: For the upper teeth, d1 - d0 was different between both groups while f1 - f0 was not statistically different. For the lower teeth, d1 - d0 was statistically different between both groups while f1 - f0 was not statistically different. Qualitative analysis: For the teeth that had no dehiscence before treatment, G2 and G4 had a better transition than did G1 and G3. For those having dehiscence before treatment, G4 had a better transition than did G3. For teeth having no fenestration before treatment, there was no statistically significant difference in transition between the control and treatment groups. For those having fenestration before treatment, G4 had a better transition than did G3. CONCLUSIONS: For skeletal class III patients, augmented corticotomy-assisted orthodontic treatment is a promising method of improving alveolar bone dehiscence and fenestration for lower anterior teeth, and it also has the potential to protect both lower and upper anterior teeth against dehiscence.
An in vivo and cone beam computed tomography investigation of the accuracy in measuring alveolar bone height and detecting dehiscence and fenestration defects
[J].PURPOSE: To investigate cone beam computed tomography (CBCT) accuracy in measuring facial bone height and detecting dehiscence and fenestration defects around teeth. MATERIALS AND METHODS: Patients who were treatment planned for periodontal flap or dental implant surgeries were enrolled (n = 25). CBCT imaging (Carestream CS 9300) was obtained at 0.09-mm voxels (n = 10 patients, 23 teeth) and at 0.18-mm voxels (n = 15 patients, 33 teeth). Facial bone height measurements, from cusp tip to crest of bone height along the long axis of the tooth, and presence or absence of dehiscence or fenestration defects were recorded from CBCT images in triplicates independently by two examiners. The corresponding clinical measurements were made at the time of surgery. Comparisons of CBCT and clinical measurements were made using paired t tests for teeth: anterior and posterior, maxillary and mandibular, with or without restorations, or root canal therapy. Level of agreement between investigators was assessed by concordance correlation coefficients (CCC), Pearson's correlation coefficient (PCC), and Cohen's Kappa. RESULTS: Comparing mean CBCT and clinical measurements, statistically significant differences were noted for 0.09-mm and 0.18-mm voxel sizes, for anterior and posterior teeth, for maxillary and mandibular teeth, for teeth with or without restorations, and for teeth without root canal therapy (P < .05). Clinical and CBCT measurements were similar for teeth with crowns and with root canal therapy (P > .05). CBCT measurements underestimated mean facial bone height from 0.33 +/- 0.78 to 0.88 +/- 1.14 mm (mean +/- SD) and absolute facial bone height values from 0.56 +/- 0.35 to 1.08 +/- 0.92 mm. Intraexaminer and interexaminer reliability for measuring facial bone height ranged from poor to substantial (PCC = 0.78 to 0.97 and CCC = 0.63 to 0.96, respectively). Interexaminer reliability for detection of dehiscence and fenestration defects ranged from poor to moderate (Cohen's Kappa = -0.09 to 0.66). CONCLUSION: CBCT imaging underestimated facial bone height and overestimated the presence of dehiscence and fenestration defects.
Histological evaluation of osteochondral defects: consideration of animal models with emphasis on the rabbit, experimental setup, follow-up and applied methods
[J].
Morphologic evaluation of dentoalveolar structures of mandibular anterior teeth during augmented corticotomy-assisted decompensation
[J].INTRODUCTION: Our aim in this study was to evaluate the effect of augmented corticotomy on the decompensation pattern of mandibular anterior teeth, alveolar bone, and surrounding periodontal tissues during presurgical orthodontic treatment. METHODS: Thirty skeletal Class III adult patients were divided into 2 groups according to the application of augmented corticotomy labial to the anterior mandibular roots: experimental group (with augmented corticotomy, n = 15) and control group (without augmented corticotomy, n = 15). Lateral cephalograms and cone-beam computed tomography images were taken before orthodontic treatment and before surgery. The measurements included the inclination and position of the mandibular incisors, labial alveolar bone area, vertical alveolar bone height, root length, and alveolar bone thickness at 3 levels surrounding the mandibular central incisors, lateral incisors, and canines. RESULTS: The mandibular incisors were significantly proclined in both groups (P <0.001); however, the labial movement of the incisor tip was greater in the experimental group (P <0.05). Significant vertical alveolar bone loss was observed only in the control group (P <0.001). The middle and lower alveolar thicknesses and labial alveolar bone area increased in the experimental group. In the control group, the upper and middle alveolar thicknesses and labial alveolar bone area decreased significantly. There were no significant differences in dentoalveolar changes between the 3 kinds of anterior teeth in each group, except for root length in the experimental group (P <0.05). CONCLUSIONS: Augmented corticotomy provided a favorable decompensation pattern of the mandibular incisors, preserving the periodontal structures surrounding the mandibular anterior teeth for skeletal Class III patients.
Guided bone regeneration with collagen membranes and particulate graft materials: a systematic review and meta-analysis
[J].PURPOSE: The aim of this meta-analysis was to evaluate different methods for guided bone regeneration using collagen membranes and particulate grafting materials in implant dentistry. MATERIALS AND METHODS: An electronic database search and hand search were performed for all relevant articles dealing with guided bone regeneration in implant dentistry published between 1980 and 2014. Only randomized clinical trials and prospective controlled studies were included. The primary outcomes of interest were survival rates, membrane exposure rates, bone gain/defect reduction, and vertical bone loss at follow-up. A meta-analysis was performed to determine the effects of presence of membrane cross-linking, timing of implant placement, membrane fixation, and decortication. RESULTS: Twenty studies met the inclusion criteria. Implant survival rates were similar between simultaneous and subsequent implant placement. The membrane exposure rate of cross-linked membranes was approximately 30% higher than that of non-cross-linked membranes. The use of anorganic bovine bone mineral led to sufficient newly regenerated bone and high implant survival rates. Membrane fixation was weakly associated with increased vertical bone gain, and decortication led to higher horizontal bone gain (defect depth). CONCLUSION: Guided bone regeneration with particulate graft materials and resorbable collagen membranes is an effective technique for lateral alveolar ridge augmentation. Because implant survival rates for simultaneous and subsequent implant placement were similar, simultaneous implant placement is recommended when possible. Additional techniques like membrane fixation and decortication may represent beneficial implications for the practice.
Evaluation of maxillary sinus anatomical variations and lesions: a retrospective analysis using cone beam computed tomography
[J].
Cortical or trabecular bone: what’s the difference?
[J].
Tooth movement through the maxillary sinus
[J].
Treatment of class II malocclusion with tooth movement through the maxillary sinus
[J].This case report describes the successful extraction treatment of a Class II malocclusion with excessive maxillary sinus pneumatization. A 20-year-old man sought treatment with the major complaint of protrusive mouth and anterior teeth. He was diagnosed with a skeletal Class II relationship and protrusion of the maxilla. The clinical examination showed a severe Class II molar relationship with excessive overjet and deep overbite. Panoramic radiograph showed obvious maxillary sinus pneumatization bilaterally. Three premolars and one deciduous molar were extracted, and spaces were used to correct molar relationship and retract maxillary incisors. Light forces and low speed movement were applied to overcome the challenge of moving teeth through the maxillary sinus wall. Balanced facial esthetic and stable occlusion were obtained posttreatment with a notable bone formation of the maxillary sinus wall. This result highlights the possibility of tooth movement through cortical floor with bone remodeling and no obvious complications.
Sequelae of delayed replantation of maxillary permanent incisors after avulsion: a case series with 24-month follow-up and clinical review
[J].Replantation of avulsed incisors in young children is a successful treatment modality. Almost all replanted teeth exhibit ankylosis followed by inflammatory or replacement resorption, as immediate replantation is practically rare. The purpose of the review is to report a series of cases of prolonged delay in replantation of avulsed incisors and discuss its sequelae, leading to different patterns of root resorption after a minimum follow-up period of 24 months. The present case series is a follow-up of five cases of delayed replantation (more than 24 h delay) without any root surface treatment. Extraoral endodontic therapy was performed before replantation. The avulsed teeth were stabilized using an acid-etch composite resin splint for 4 weeks. The patients were followed up at 3, 6, and 12 months interval and half-yearly thereafter, for examination of the replanted teeth clinically and radiographically. After 24-month follow-up, the replanted teeth were evaluated for gingival changes and clinical mobility. The radiographs were evaluated for external root resorption or inflammatory resorption, osseous root replacement, or replacement resorption. The case series concludes that avulsed teeth transported in dry as well as dessicated conditions and replanted after a delay of 24 h have a survival rate of more than 24 months, though there is no promising long-term prognosis. The sequelae in most of the cases are surface resorption followed by inflammatory resorption or resorption due to pulpal infection or replacement resorption.
Effectiveness of decoronation technique in the treatment of ankylosis: a systematic review
[J].BACKGROUND: Dentoalveolar ankylosis in growing patients is complex leading to continuing root replacement resorption, tooth infra-position, or may even affect the development of alveolar ridge and adjacent teeth. While extraction of ankylosed teeth might be associated with bone loss, decoronation of the offending tooth (removal of crown portion and instrumentation of pulp canal to stimulate bleeding) has been suggested as a more conservative approach of bone preservation until definitive implant placement is planned. OBJECTIVE: To primarily assess the efficacy of bone width and height preservation around ankylosed permanent teeth following decoronation. METHODS: Pubmed, Embase, Ovid Medline, Thomson's ISI Web of Science and Cochrane library were searched from the year 1984 up to May 2015. Two authors conducted the data extraction. To eliminate publication bias, Open Grey literature and Pro-quest Dissertation Abstracts and Thesis database was also consulted. RESULTS: Through our strict selection criteria, only 12 articles were considered for eligibility. No randomized controlled trials were identified. Only one retrospective cohort study, four case series and seven case reports, were analyzed. CONCLUSIONS: Following decoronation, preservation of ridge height and ridge width were both noted. To maximize the benefits of decoronation, a timely and wellmonitored intervention is required. Treatment in patients, who have surpassed pubertal growth peaks, may not yield maximum effective treatment outcomes.
Impacted maxillary canines and root resorption of adjacent teeth: a retrospective observational study
[J].BACKGROUND: The prevalence of impacted maxillary canine is reported to be between 1% and 3%. The lack of monitoring and the delay in the treatment of the impacted canine can cause different complications such as: displacement of adjacent teeth, loss of vitality of neighbouring teeth, shortening of the dental arch, follicular cysts, canine ankylosis, recurrent infections, recurrent pain, internal resorption of the canine and the adjacent teeth, external resorption of the canine and the adjacent teeth, combination of these factors. An appropriate diagnosis, accurate predictive analysis and early intervention are likely to prevent such undesirable effects. The objective is to evaluate, by means of a retrospective observational study, the possibility of carrying out a predictive analysis of root resorption adjacent to the impacted canines by means of orthopantomographs, so as to limit the prescription of additional 3D radiography. MATERIAL AND METHODS: 120 subjects with unilateral or bilateral maxillary impacted canine were examined and 50 patients with 69 impacted maxillary canine (22 male, 28 female; mean age: 11.7 years) satisfied the inclusion criteria of the study. These patients were subjected to a basic clinical and radiographic investigation (orthopantomographs and computerized tomography). All panoramic films were viewed under standardized conditions for the evaluation of two main variables: maxillary canine angulations (a, b, g angles) and the overlapping between the impacted teeth and the lateral incisor (Analysis of Lindauer). Binary logistic regression was used to estimate the likelihood of resorbed lateral incisors depending on sector location and angle measurements. RESULTS: Results indicated that b angle has the greatest influence on the prediction of root resorption (predictive value of b angle = 76%). If beta angle <18 degrees and Lindauer = I, the probability of resorption is 0.06. CONCLUSIONS: Evaluation of b angle and superimposition lateral incisor/impacted canine analysed on orthopantomographs could be one of the evaluation criteria for prescribing second level examination (CT and CTCB) and for detecting root resorption of impacted maxillary canine adjacent teeth.
Accroissements gingivaux: approche pragmatique[Gingival enlargement: practical management]
[J].
Gingival invagination--a systematic review
[J].Gingival invagination is an alteration of the ginviva often observed during orthodontic space closure. This finding appears as a
Association between facial growth pattern and facial muscle activity: a prospective cross-sectional study
[J].OBJECTIVE: To evaluate the relationship between facial growth pattern and electromyography (EMG) of facial muscles: anterior temporalis, masseter, buccinators, orbicularis oris, mentalis and anterior digastric. PATIENTS AND METHODS: The sample consisted of 77 subjects aged between 18-28 years (mean age 21.10+/-2.03), with dental Class I relationship, normal overjet and overbite, balanced facial profile, no signs of temporomandibular disorders, and no previous orthodontic treatment. Facial growth pattern was determined on the lateral cephalograms according to the Bjork sum (sum of the N-S-Ar, S-Ar-Go, and Ar-Go-Me angles) dividing the sample into three groups: horizontal facial pattern group (24 subjects), normal facial pattern group (41 subjects), and vertical facial pattern group (12 subjects). The EMG of anterior temporalis, masseter, buccinator, orbicularis oris, mentalis and anterior digastric muscles were examined for each patient in the rest position and in functional positions (central maximum intercuspation, chewing on right side, chewing on left side and swallowing). Mean values and standard deviation of EMG were obtained and compared between the three groups. RESULTS: At rest, the EMG of the masseter, orbicularis oris and anterior digastric were higher in the vertical facial pattern group compared with the other two groups, with a moderate positive correlation between the EMG of these muscles and the Bjork sum (P<.01). In contrast, during central maximum intercuspation, the activity of the anterior temporalis, masseter and buccinator was significantly lower in the vertical facial pattern group compared with the two other groups, with a moderate negative correlation between the Bjork sum and EMG in the maximum central intercuspation position of these muscles (P<.01). CONCLUSIONS: A significant relationship was found between facial muscle activity and facial growth pattern. The findings suggest that the activity of masticatory and perioral muscles could play a role in the direction of the facial growth.
Comparison of anterior mandibular alveolar thickness and height in young adults with different sagittal and vertical skeletal relationships: a CBCT Study
[J].OBJECTIVE: Alveolar bone surrounding mandibular incisors dictates the range of buccolingual inclination that can be achieved with treatment. The objective of this study was to evaluate the mandibular anterior alveolar thickness and height in individuals with different sagittal and vertical skeletal relationships. MATERIALS AND METHODS: Cone beam computed tomography scans of 53 individuals (22 males and 31 females; mean age 21.19+/-3.7 years) were classified into 3 groups according to the sagittal skeletal relationship (class I, class II, and class III) and the vertical growth pattern (hyperdivergent, normodivergent, and hypodivergent). The alveolar thickness and height of both mandibular central incisors were measured. Group comparisons were performed with analysis of variance and post hoc Scheffe tests. Multiple linear regression was applied to evaluate the influence of all variables on the alveolar conditions. RESULTS: Alveolar thickness and height showed no significant differences among the class I, II and III groups (6 and 7mm regardless of the sagittal group, P>0.05). The middle and lower alveolar thicknesses were significantly smaller in hyperdivergent (5.76mm and 6.34mm) and normodivergent (6.29mm and 7.40mm) than hypodivergent individuals (6.63mm and 8.27mm respectively). The lingual alveolar height was smaller in hyperdivergent (6.04mm) than hypodivergent individuals (7.93mm) (P=0.029, 95%CI: 0.15-3.63) and the lingual bone height was smaller in hypodivergent (3.24mm) than hyperdivergent individuals (5.06mm) (P=0.029, 95%CI: 0.15-3.48). Multiple linear regression indicated a significant influence of the root length on the alveolar thickness and height. CONCLUSIONS: The sagittal skeletal relationship showed no influence on the alveolar thickness or height, even if dental compensation was present. Hyperdivergent individuals showed smaller alveolar thicknesses and heights than hypodivergent individuals.
Methods of accelerating orthodontic tooth movement: a review of contemporary literature
[J].Technological progress and the introduction of modern therapeutic methods are constantly changing contemporary orthodontics. More and more orthodontic patients are working adults, who expect satisfactory therapeutic effects as soon as possible, increasing the importance of methods accelerating tooth movement. The aim of this study was to review the current literature regarding methods of accelerating tooth movement and reducing the duration of the active phase of therapy. The literature was collected from the PubMed and EBSCO databases using
Occlusal trauma and excessive occlusal forces: narrative review, case definitions, and diagnostic considerations
[J].
Factors related to the rate of orthodontically induced tooth movement
[J].INTRODUCTION: The purpose of this study was to investigate the variations of orthodontically induced tooth movement in the maxillary and mandibular arches between patients and the factors such as age, sex, and presence of an interference that might influence the amount of tooth displacement. METHODS: By using a standardized experimental orthodontic tooth movement in 30 subjects, 57 premolars were moved buccally during 8 weeks with the application of a 1-N force. Forty-four contralateral premolars not subjected to orthodontic tooth movement served as the controls. Plaster models from before and after the experimental tooth movement were digitized and superimposed to evaluate the amounts of tooth movement. Differences in tooth movement between the experimental and control groups were tested by an unpaired t test. For the experimental teeth, subject-related factors (age and sex) and tooth-related factors (location in the maxillary or mandibular dental arch, and the presence or absence of an intra-arch or interarch obstacle such as neighboring touching teeth or teeth interfering with the occlusion) were examined with analysis of variance. Multiple linear regression analysis was performed to determine correlations between tooth displacement, age, sex, tooth location, and presence of an interference. RESULTS: Each subject contributed at least 2 experimental premolars and 1 control premolar. The displacement of the orthodontically moved teeth was 2.42 mm (range, 0.3-5.8 mm). Younger subjects (<16 years; n = 19; number of teeth, 36) had significantly greater amounts of tooth displacement compared with older subjects (>/=16 years; n = 11; number of teeth, 21): 2.6 +/- 1.3 mm vs 1.8 +/- 0.8 mm; P <0.01. When an interarch or intra-arch obstacle was present, the amount of tooth movement was significantly less (2.6 +/- 1.3 mm vs 1.8 +/- 0.8 mm) (P <0.05). Neither sex nor the location of the experimental teeth in the mandible or the maxilla had any effect. CONCLUSIONS: Younger patients showed greater tooth movement velocity than did older ones. An interarch or intra-arch obstacle decreased the amount of tooth displacement.
An incidental dense bone island: a review of potential medical and orthodontic implications of dense bone islands and case report
[J].Dense bone islands (DBIs) are usually asymptomatic and do not require any treatment. This case report presents a DBI of an unusual presentation, which was an incidental finding on a radiograph of a 15-year-old orthodontic patient. The DBI lesion was 24 mm in size, occupying at least 50% of the alveolar process between the upper right canine and lateral incisor, extending up the lateral aspect of the anterior margin of the right nasal fossa. Generally, DBIs are 2-3 mm in size and more commonly found in the mandible in the molar and premolar region. This article further discusses the impact of DBIs on orthodontic treatment such as difficulty with achieving space closure and adequate root tip or torque. We also examine the potential medical implications of DBIs. This is clinically important, especially if multiple DBIs, or osteomas which have a similar radiographic appearance to DBIs, are found in a patient as they may be associated with adenomatous intestinal polyps, which, if not treated, have a 100% chance of becoming malignant transformation.
Relative kinetic frictional forces between sintered stainless steel brackets and orthodontic wires
[J].The level of kinetic frictional forces generated during in vitro translation at the bracket-wire interface were measured for two sintered stainless steel brackets as a function of two slot sizes, four wire alloys, and five to eight wire sizes. The two types of sintered stainless steel brackets were tested in both 0.018-inch and 0.022-inch slots. Wires of four different alloy types, stainless steel (SS), cobalt chromium (Co-Cr), nickel-titanium (Ni-Ti), and beta-titanium (beta-Ti), were tested. There were five wire sizes for the 0.018-inch slot and eight wire sizes for the 0.022-inch slot. The wires were ligated into the brackets with elastomeric ligatures. Bracket movement along the wire was implemented by means of a mechanical testing instrument, and time dependent frictional forces were measured by a load cell and plotted on an X-Y recorder. For most wire sizes, lower frictional forces were generated with the SS of Co-Cr wires than with the beta-Ti or Ni-Ti wires. Increase in wire size generally resulted in increased bracket-wire friction. There were no significant differences between manufacturer for the sintered stainless steel brackets. The levels of frictional force in 0.018-inch brackets ranged from a low of 46 gm with 0.016-inch Co-Cr wire to a high of 157 gm with 0.016 x 0.025-inch beta-Ti wire. In comparing the data from a previous study by Kapila et al. 1990 performed at OUHSC with the same apparatus, the friction of sintered stainless steel brackets was approximately 40% to 45% less than the friction of the conventional stainless steel brackets.
Transversal changes, space closure, and efficiency of conventional and self-ligating appliances: a quantitative systematic review
[J].OBJECTIVE: Self-ligating brackets (SLBs) were compared to conventional brackets (CBs) regarding their effectiveness on transversal changes and space closure, as well as the efficiency of alignment and treatment time. METHODS: All previously published randomized controlled clinical trials (RCTs) dealing with SLBs and CBs were searched via electronic databases, e.g., MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, World Health Organization International Clinical Trials Registry Platform, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure. In addition, relevant journals were searched manually. Data extraction was performed independently by two reviewers and assessment of the risk of bias was executed using Cochrane Collaboration's tool. Discrepancies were resolved by discussion with a third reviewer. Meta-analyses were conducted using Review Manager (version 5.3). RESULTS: A total of 976 patients in 17 RCTs were included in the study, of which 11 could be produced quantitatively and 2 showed a low risk of bias. Meta-analyses were found to favor CB for mandibular intercanine width expansion, while passive SLBs were more effective in posterior expansion. Moreover, CBs had an apparent advantage during short treatment periods. However, SLBs and CBs did not differ in closing spaces. CONCLUSIONS: Based on current clinical evidence obtained from RCTs, SLBs do not show clinical superiority compared to CBs in expanding transversal dimensions, space closure, or orthodontic efficiency. Further high-level studies involving randomized, controlled, clinical trials are warranted to confirm these results.
Contemporary orthodontics
[M].
Effect of continuous versus intermittent orthodontic forces on root resorption: a microcomputed tomography study
[J].OBJECTIVES:: To compare the extent of root resorption and the amount of tooth movement between continuous orthodontic force and intermittent orthodontic force that was activated in a similar way to a 4-week orthodontic adjustment period. MATERIALS AND METHODS:: Twenty-five patients who required the extraction of upper first premolars were recruited in this study. A buccally directed continuous force of 150 g was applied to the upper first premolar on one side for 15 weeks. A buccally directed intermittent force (28 days on, 7 days off) of the same magnitude was applied to the contralateral first premolar. The teeth were extracted at the end of the experimental period and processed for volumetric evaluations of resorption craters. The degree of tooth movement and rotation were measured on the study models. RESULTS:: Continuous force application displayed significantly higher root resorption volume than the intermittent force application ( P < .05), particularly on the buccal and lingual surfaces (P < .05) and the middle third of the root ( P < .01). There was more tipping and rotational movement in the continuous force group. CONCLUSIONS:: In a 4-week orthodontic adjustment period, intermittent force significantly reduced the amount of root resorption compared with continuous force. Although there was less degree of tooth movement with intermittent force, unwanted rotational movement was avoided. This is crucial in patients who are predisposed to orthodontically induced inflammatory root resorption, and the use of this intermittent regimen should be considered.
Age effect on orthodontic tooth movement rate and the composition of gingival crevicular fluid: a literature review
[J].
Biological mechanisms of tooth movement
[M].
Vitamin C and eggshell membrane facilitate orthodontic tooth movement and induce histological changes in the periodontal tissue
[J].OBJECTIVES: Collagen remodeling of the periodontal tissue is an important mechanism that involves several biologically active substances to accelerate orthodontic tooth movement. It is known that Vitamin C (VC) enhances collagen production and induces tooth movement. Moreover, the eggshell membrane (ESM) is an integral component of various formulations used to promote wound healing. The purpose of our study was to determine the effects of combined treatment with VC and ESM on periodontal tissues during tooth movement. METHODS: Nine-week-old male osteogenic disorder Shionogi rats were randomized into four groups: control, VC, ESM, and VC + ESM. The control group was given tap water, and the VC, ESM, and VC + ESM groups were orally administered 0.1% VC solution, 1 wt% ESM solution, and a combination of 0.1 wt% VC and 1 wt% ESM solutions, respectively. A force of 25 or 75 g was applied for 10 days to produce orthodontic tooth movement. Distances of tooth movement were measured on days 3, 7, and 10 of treatment. Histological examination of the periodontal ligament was performed to determine the increase in type I and III collagen levels in response to treatment. RESULTS: Distances of tooth movement were significantly greater in the VC + ESM group than in the control group. The compression area of the alveolar bone showed increased osteoclastic activity and higher levels of bone resorption in the VC + ESM group. Expression levels of type I and III collagen in the tension area of the alveolar bone were higher in the VC + ESM group than in the control group. CONCLUSIONS: This study revealed that the combined administration of VC and ESM accelerated tooth movement by protecting the periodontal tissue during orthodontic treatment. The combined clinical application of VC and ESM could potentially shorten orthodontic treatment time.
Effect of statins on orthodontic tooth movement: a systematic review of animal and clinical studies
[J].OBJECTIVE: The objective was to systematically-review the effect of statin drugs on orthodontic-tooth-movement (OTM). DESIGN: The focused-question was
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