液氮冷冻治疗婴幼儿唇黏膜静脉畸形的效果观察

doi:10.12016/j.issn.2096-1456.2016.02.007

口腔疾病防治 ›› 2016, Vol. 24 ›› Issue (2): 98-100.DOI: 10.12016/j.issn.2096-1456.2016.02.007

所属专题： 111

液氮冷冻治疗婴幼儿唇黏膜静脉畸形的效果观察

万荻,张大明,庄沛林,王友元,林钊宇,张彬(),陈伟良

中山大学孙逸仙纪念医院口腔颌面外科,广东广州(510120)

收稿日期:2015-08-16 修回日期:2015-09-28 出版日期:2016-02-20 发布日期:2016-02-20
通讯作者: 张彬
作者简介:万荻,医师,硕士研究生, Email: 525882833@qq.com
基金资助:
国家自然科学基金(81072229)

Liquid nitrogen cryotherapy of infant lip mucosa venous malformations

Di WAN,Da-ming ZHANG,Pei-lin ZHUANG,You-yuan WANG,Zhao-yu LIN,Bin ZHANG(),Wei-liang CHEN

Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China

Received:2015-08-16 Revised:2015-09-28 Online:2016-02-20 Published:2016-02-20
Contact: Bin ZHANG

摘要/Abstract

摘要：

目的探讨液氮冷冻治疗婴幼儿唇黏膜静脉畸形的效果。方法 57例唇黏膜静脉畸形患儿采用液氮冷冻治疗。男35例,女22例,平均年龄7.4个月。术前、术后及每次复诊拍照记录,对治疗结果进行评估。结果随访2~16个月,71.9%(41/57)完全有效,19.3%(11/57)明显有效,8.8%(5/57)部分有效。所有病例均未出现严重并发症。结论液氮冷冻治疗唇黏膜静脉畸形安全、有效。

关键词: 唇黏膜, 静脉畸形, 冷冻治疗, 婴幼儿, 液氮

Abstract:

Objective To explore the reliability of liquid nitrogen cryotherapy for infant lip mucosa venous malformations.Methods A retrospective review of 57 pediatric patients with venous malformations involving the lips who underwent liquid nitrogen cryotherapy was enrolled in. Among them, 35 patients were males and 22 patients were females; the age of the patients ranged from 3 to 21 months (average 7.4 months). Photographs were taken preoperatively, immediately postoperatively and one month postoperatively. Following up period was 2-16 months and the outcome was assessed.Results 71.9% cases were completely effective, 19.3% cases were mostly effective, 8.8% cases were partially effective. No cases showed the anesthesia complications.Conclusion Liquid nitrogen cryotherapy is an effective, simple and safe treatment for lip mucous venous malformations.

Key words: Lip mucosa, Venous malformations, Cryotherapy, Infancy, Liquid nitrogen

中图分类号:

R782.2

万荻,张大明,庄沛林,王友元,林钊宇,张彬,陈伟良. 液氮冷冻治疗婴幼儿唇黏膜静脉畸形的效果观察[J]. 口腔疾病防治, 2016, 24(2): 98-100.

Di WAN,Da-ming ZHANG,Pei-lin ZHUANG,You-yuan WANG,Zhao-yu LIN,Bin ZHANG,Wei-liang CHEN. Liquid nitrogen cryotherapy of infant lip mucosa venous malformations[J]. Journal of Prevention and Treatment for Stomatological Diseases, 2016, 24(2): 98-100.

图/表 1

参考文献 12

[1]	Buckmiller LM, Richter GT, Suen JY . Diagnosis and management of hemangiomas and vascular malformations of the head and neck[J]. Oral Dis, 2010,16(5):405-418. DOI URL PMID
[2]	Zheng JW, Mai HM, Zhang L , et al. Guidelines for the treatment of head and neck venous malformations[J]. Int J Clin Exp Med, 2013,6(5):377-389. DOI URL
[3]	张大明, 柴强, 陈伟良 , 等. 婴幼儿唇粘膜血管瘤的液氮冷冻治疗[J]. 中国口腔颌面外科杂志, 2010,4(8):300-303.
[4]	Chen WL, Zhang B, Li JS , et al. Liquid nitrogen cryotherapy of lip mucosa hemangiomas under inhalation general anesthesia with sevoflurane in early infancy[J]. Ann Plast Surg, 2009,62(2):154-157. DOI URL
[5]	Chen WL, Yang ZH, Bai ZB , et al. A pilot study on combination compartmentalisation and sclerotherapy for the treatment of massive venous malformations of the face and neck[J]. Plast Reconstr Aesthet Surg, 2008,61(12):1486-1492. DOI URL PMID
[6]	Redondo P . Vascular malformations: concept, classification, pathogenesis and clinical features[J]. Actas Dermosifiliogr, 2007,98(3):141-158. DOI URL
[7]	Zheng JW, Yang XJ, Wang YA , et al. Intralesional injection of Pingyangmycin for vascular malformations in oral and maxillofacial regions: an evaluation of 297 consecutive patients[J]. Oral Oncol, 2009,45(10):872-876. DOI URL PMID
[8]	Chen WL, Huang ZQ, Zhang DM , et al. Percutaneous sclerotherapy of massive venous malformations of the face and neck using fibrin glue combined with OK-432 and pingyangmycin[J]. Head Neck, 2010,32(4):467-472. DOI URL PMID
[9]	宾志文 . 平阳霉素注射治疗口腔颌面部低回流型静脉畸形[J]. 广东牙病防治, 2013,21(9):474-476.
[10]	吕维敏, 姜红强, 黄钢妹 , 等. 医用低温温度标定方法[J]. 低温与超导, 2013,41(11):43-46.
[11]	Najarian DJ, Rao BK, Pappert AS . A case of mucous membrane plasmacytosis successfully treated with cryotherapy[J]. Dermatol Online J, 2008,14(2):6. URL PMID
[12]	Moraes PC, Teixeira RG, Thomaz LA . Liquid nitrogen cryosurgery for treatment of mucoceles in children[J]. Pediatr Dent, 2012,34(2):159-161.

液氮冷冻治疗婴幼儿唇黏膜静脉畸形的效果观察

Liquid nitrogen cryotherapy of infant lip mucosa venous malformations

RichHTML

PDF

可视化

摘要/Abstract

引用本文

使用本文

图/表 1

参考文献 12

相关文章 11

编辑推荐

Metrics

[1]	李芳芳,孟箭,庄乾伟. 聚多卡醇经皮硬化治疗成人巨大唇颊部微静脉畸形[J]. 口腔疾病防治, 2021, 29(9): 611-616.
[2]	杨慧,王翔,张磊,王文梅,段宁,李若玮,张苗苗. 19例口腔黏膜恶性黑色素瘤临床分析[J]. 口腔疾病防治, 2021, 29(12): 843-847.
[3]	郑家伟,赵泽亮. 婴幼儿血管瘤与脉管畸形的循证治疗研究进展[J]. 口腔疾病防治, 2021, 29(11): 721-732.
[4]	李瑞春,景凯岸,王丽娜,马瑞,景捷,马坚. 下颌下腺导管畸形伴多发结石病例报道及文献复习[J]. 口腔疾病防治, 2020, 28(2): 93-96.
[5]	周万航,李嫣斐,张媛媛. 疱疹性咽峡炎与手足口病的相关性研究进展[J]. 口腔疾病防治, 2020, 28(1): 61-64.
[6]	郑家伟,赵泽亮. 血管瘤和脉管畸形的遗传学研究进展[J]. 口腔疾病防治, 2019, 27(12): 749-756.
[7]	李嘉朋,陈巨峰,张国润,冼淡,李金,王磊,张国义. 口服普萘洛尔联合局部外用马来酸噻吗洛尔治疗婴幼儿颌面部混合性血管瘤的临床效果[J]. 口腔疾病防治, 2019, 27(11): 718-722.
[8]	邓佳欣,陈悦,陈媛,王艳. 口腔颌面部血管瘤治疗的研究进展[J]. 口腔疾病防治, 2019, 27(1): 50-55.
[9]	陶小安, 程斌. 口腔扁平苔藓治疗现状分析[J]. 口腔疾病防治, 2018, 26(3): 143-150.
[10]	陆洋, 刘爱宾, 林丹丹. 就诊时机与儿童初诊牙科焦虑的相关性分析[J]. 口腔疾病防治, 2017, 25(3): 188-191.
[11]	吴晓平,张大明,陈伟良. 口服普萘洛尔治疗婴幼儿头颈部血管瘤的临床效果观察[J]. 口腔疾病防治, 2016, 24(3): 158-161.