doi:10.12016/j.issn.2096-1456.2016.05.013

Abstract

摘要：

牙周膜干细胞(periodontal ligament stem cells,PDLSCs)被认为是牙周组织工程理想的种子细胞,具有多向分化潜能。间充质干细胞在成脂和成骨分化过程中具有相互制约的平衡关系,成脂分化的诱导因素通常是成骨分化的抑制因素,反之亦然。本文就近年来PDLSCs成脂分化的诱导、鉴定方法及相关转录因子的研究进展进行综述,分析PDLSCs成脂分化的机制,探讨通过抑制PDLSCs成脂分化促进其成骨分化的可行性,为治疗牙槽骨吸收等骨骼性疾病提供参考。

关键词: 牙周膜干细胞, 脂肪样细胞, 检测, 转录因子, 成脂分化, 成骨分化

CLC Number:

R781.4

李夏宁综述,赵红宇,赵华审校. 牙周膜干细胞成脂分化的研究进展[J]. 口腔疾病防治, 2016, 24(5): 317-320.

References 29

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牙周膜干细胞成脂分化的研究进展

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