Journal of Prevention and Treatment for Stomatological Diseases ›› 2016, Vol. 24 ›› Issue (7): 416-419.doi: 10.12016/j.issn.2096-1456.2016.07.008

• Cinical Study • Previous Articles     Next Articles

Use cervical vertebra bone age to evaluate the development situation of unilateral complete cleft lip and palate patients

Na JIN,Cun-hui FAN(),Tao XU,Li-xia YANG,Hong-yang WANG,Xue-fang ZHAO   

  1. Department of Orthodontics, the Affiliated Hospital of Qingdao University, Qingdao 266003, China
  • Received:2016-01-06 Revised:2016-02-23 Online:2016-07-20 Published:2016-07-20
  • Contact: Cun-hui FAN


Objective Use cervical vertebra bone age to assess the development situation of the patients with unilateral complete cleft lip and palate (UCLP).Methods A total of 45 UCLP patients aged 9 to 16 years were selected as experimental group. Another 45 patients of the same age and race without cleft lip and palate were selected as control group. Lateral cephalometric radiographs were taken for the patients. Lateral cephalometric radiographs were used to measure and calculate vertebra bone of the UCLP group and the Non-cleft group. Independent samples t test was used to compare bone age of UCLP group and the Non-cleft group in same gender.Results Cervical vertebra bone age of male patients in UCLP group was significantly smaller than patients in the Non-cleft group (P < 0.05), while cervical vertebra bone age of female patients shows no significant difference between two groups (P > 0.05).Conclusion Compared with Non-cleft patients, the male UCLP patients' development is relatively slow. And there is no significant difference between the female patients in two groups.

Key words: Cleft lip and palate, Cervical vertebra bone age, Development, Lateral cephalometric radiograph, Cephalometric analysis

CLC Number: 

  • R783
[1] 杨媛媛, 黄素华, 黄孟燕 , 等. 先天性唇腭裂949例临床资料回顾分析[J]. 广西医学, 2014,44(3):309-311.
doi: 10.11675/j.issn.0253-4304.2014.03.12
[2] 许小幸, 周晓彬, 张东峰 , 等. 青岛市区3~7岁儿童生长发育指数调查[J]. 青岛大学医学院学报, 1999,35(1):47-48.
doi: 10.3969/j.issn.1672-4488.1999.01.019
[3] 郭鹏, 孙艳环 . 3 ~ 7岁农村儿童生长发育状况调查[J]. 青岛大学医学院学报, 2000,36(3):221-222.
doi: 10.3969/j.issn.1672-4488.2000.03.030
[4] 罗家燕 . 骨龄评价与儿童生长发育[J]. 国外医学.口腔医学分册, 1998,25(2):96-99.
[5] Mito T, Satok J, Mitani H . Cervical vertebral bone age in girls[J]. Am J Orthod Dent of acial Orthop, 2002,122(4) : 380-385.
doi: 10.1067/mod.2002.126896 pmid: 12411883
[6] Kucukkeles N, Acar A . Comparisions between cervical vert ebrae and hand-wrist maturation for the assessment of skelet al maturity[J]. JCl in Pediatr Dent, 1999,24(1):47.
[7] Chang HP, Liao CH, Yang YH , et al. Correlation of cervical vertebra maturation with hand-wrist maturation in children[J]. Kaohsiung J Medical Sciences, 2001,17(1):5462-5465.
doi: 10.1016/j.bmcl.2010.07.094 pmid: 11411257
[8] 苏莉, 吕婴, 王红梅 . 青春发育期颈椎骨龄计算方法的探讨[J]. 中华口腔医学杂志, 2006,41(12):728-729.
doi: 10.3760/j.issn:1002-0098.2006.12.007
[9] 程敏, 马晓晴, 邹淑娟 . 单侧完全性唇腭裂患者的正畸治疗[J]. 广东牙病防治, 2008,16(4):150-153.
doi: 10.3969/j.issn.1006-5245.2008.04.002
[10] 谢吉晔, 许艳华 . 颌面部软组织侧貌的美学研究进展[J]. 广东牙病防治, 2015,23(4):219-222.
[11] O'Reilly MT, Yanniello GJ . Mandibular growth changes and maturation of cervical vertebrae—a longitudinal cephalometric study[J]. Angle Orthod, 1988,58(2):179-184.
doi: 10.1043/0003-3219(1988)0582.0.CO;2 pmid: 3164596
[12] 李陆玥, 林久祥, 陈莉莉 . 正常颌青少年颈椎骨龄定量分析法(QCVM)的准确性和重复性探讨[J]. 口腔医学, 2013,33(4):261-264.
[13] 袁正林, 林久祥, 陈莉莉 . 基于颈椎骨龄定量分期法的上颌发育不足患者最佳矫形时机的探讨[J]. 华中科技大学学报: 医学版, 2013,42(2):156-160.
doi: 10.3870/j.issn.1672-0741.2013.02.007
[14] Borodkin AF, Feigal RJ, Beiraghi S , et al. Permanent tooth development in children with cleft lip and palate[J]. Pediatr Dent, 2008,30(5):408-413.
[15] Huyskens RW, Katsaros C, Vant Hof MA , et al. Dentalage in children with a complete unilateral cleft lip and palate[J]. Cleft Palate Craniofac J, 2006,43(5):612-615.
doi: 10.1597/05-096 pmid: 16986989
[16] 申勇, 范存晖, 杨茜 , 等. 单侧完全性唇腭裂男性患者的牙齿发育状况[J]. 山东大学学报: 医学版, 2014,52(7):99-101.
doi: 10.6040/j.issn.1671-7554.1.2014.002
[17] Ross RB . Treatment variables affecting facial growth in complete unilateral cleft lip and palate[J]. Cleft Palate J, 1987,24(1):5-77.
[18] 刘泓虎, 钱玉芬, 孙燕 , 等. 上海地区208名儿童颈椎骨成熟度的研究[J]. 上海口腔医学, 1998,7(3):167-169.
[19] 孙铁航, 薄静 . 乳牙迟脱200例的统计与分析[J]. 现代临床医学, 1980,5:162-167.
[20] 杨莽, 施星辉, 邢树忠 . 儿童上前牙区埋伏多生牙42例临床分析[J]. 现代口腔医学杂志, 1997,11(2):147-147.
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