Journal of Prevention and Treatment for Stomatological Diseases ›› 2016, Vol. 24 ›› Issue (10): 614-616.DOI: 10.12016/j.issn.2096-1456.2016.10.012

• Prevention and Treatment Practice • Previous Articles     Next Articles

Comparison of clinical effects of three different materials used in apexification

Shu-fang WANG,Ji-fang REN()   

  1. Department of Stomatology, Songjiang District Central Hospital, Shanghai 201600, China
  • Received:2015-12-04 Revised:2024-03-09 Online:2016-10-20 Published:2016-10-20
  • Contact: Ji-fang REN



  1. 上海市松江区中心医院口腔科, 上海(201600)
  • 通讯作者: 任吉芳
  • 作者简介:王淑芳,主治医师,硕士,Email:


Objective To compare the clinical effect of three different kinds of materials used in apexification.Methods Sixty immature permanent teeth with pulpitis, pulp necrosis, periapical periodontitis were selected and randomly assigned to 3 groups according to registration order. Group A was treated with mineral trioxide aggregate (MTA), group B with Vitapex, and the control group with calcium hydroxide. All patients were recalled 3, 6 and 12 months after initial treatment.Results Pearson Chi-square test showed that the efficacy rate of group A was significantly higher than group B and the control group (P<0.05) in the visits of 3 months and 6 months after treatment. And efficacy rate of group B is also higher than the control group, but no statistical difference was found between two groups in the final visit (12 months). The efficacy rate of group A is 94.1%, group B is 75.0% and the control group is 58.8%. The statistical difference was found between group A and control group, but it was not found between group A and group B or between group B and the control group.Conclusion Compared with calcium hydroxide and Viatapex, MTA for apexification has better performance in apexification.

Key words: Immature tooth, Apexification, MTA, Vitapex, Calcium hydroxide paste


目的 比较三种药物用于根尖诱导成形术的临床效果。方法 选取8~14岁患有牙髓感染、牙髓坏死或根尖周炎的患者48例共年轻恒牙60颗,根据就诊顺序随机分为三组。分别用三氧化物多聚体(mineral trioxide aggregate,MTA)(MTA组)、Vitapex(Vitapex组)、氢氧化钙糊剂(对照组)进行根尖诱导。术后3个月、6个月、12个月复查,比较其临床效果。结果 术后3个月和6个月,MTA组有效率明显高于Vitapex组和对照组,差异具有统计学意义(P<0.05);术后12个月,MTA组有效率明显优于对照组(χ 2 = 3.96),差异具有统计学意义(P<0.05),然而MTA组和Vitapex组、Vitapex组和对照组之间的差异无统计学意义(P>0.05)。结论 与氢氧化钙和Viatapex比较,MTA用于根尖诱导成形术的效果更好。

关键词: 年轻恒牙, 根尖诱导成形术, MTA, Vitapex, 氢氧化钙糊剂

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