Abstract:

Objective To study the clinical periodontal status of patients with desquamative gingivitis (DG) and analyze the factors that influence clinical periodontal indicators. Methods A purposive sampling method was used to obtain 42 subjects for a DG case group and a control group. Periodontal clinical indicators were detected, and related factors were analyzed. Results The DG patients were primarily middle-aged women. Periodontal clinical indicators were more prevalent in individuals with oral lichen planus (OLP) and mucous membrane pemphigoid (MMP) than in the control group. Probing depth (PD) (χ²=53.058, P<0.001; χ²=32.989, P<0.001), clinical attachment (χ²=30.292, P<0.001; χ²=32.470, P<0.001) and the positive rate of bleeding on probing (BOP) (χ²=50.003, P<0.001; χ²=36.236, P<0.001) were higher in the OLP and MMP group than in the control group. The time interval between the onset and treatment of DG was correlated with PD (r_s=0.523, P<0.001) and the rate of positive BOP sites (r_s=0.377, P=0.014). Conclusion Patients with DG have obvious periodontal lesions. Early medical intervention is helpful for diagnosing and treating DG-related oral and systemic disease.

Key words: Desquamative gingivitis, Oral lichen planus, Mucous membrane pemphigoid, Chronic periodontitis, Correlative factors analysis

摘要：

目的 研究剥脱性龈炎患者的临床牙周状况,探讨影响其牙周健康的临床指标的相关因素。方法 采用立意抽样,选择42例剥脱性龈炎患者为病例组,病例组经组织学和直接免疫荧光检测,25例诊断为口腔扁平苔藓（oral lichen planus,OLP）（OLP组）,17例诊断为口腔黏膜良性类天疱疮（mucous membrane pemphigoid,MMP）（MMP组）。以剥脱性龈炎患者的健康家属为对照组,检测牙周临床指标并进行相关因素分析。结果 剥脱性龈炎患者就诊以中年女性居多。OLP组、MMP组在探诊深度、临床附着水平和探诊出血阳性率方面均显著高于对照组：OLP组探诊深度（χ²=53.058, P<0.001）、临床附着水平（χ²=30.292,P<0.001）和探诊出血阳性率（χ²=50.003,P<0.001）高于对照组;MMP组探诊深度（χ²=32.989,P<0.001）、临床附着水平（χ²=32.470,P<0.001）和探诊出血阳性率（χ²=36.236,P<0.001）高于对照组。剥脱性龈炎病例发病至就诊的时间与探诊深度（r_s=0.523,P<0.001）和探诊出血阳性率（r_s=0.377,P=0.014）之间存在相关关系。结论 剥脱性龈炎患者牙周病变程度更重,需要对此类患者进行早期治疗。

关键词: 剥脱性龈炎, 口腔扁平苔藓, 良性黏膜类天疱疮, 慢性牙周炎, 相关因素分析