Journal of Prevention and Treatment for Stomatological Diseases ›› 2018, Vol. 26 ›› Issue (9): 545-550.doi: 10.12016/j.issn.2096-1456.2018.09.001

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Therapeutic progress of diabetic periodontitis

Yi DING1(),Qi WANG2   

  1. 1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
    2. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-04-09 Revised:2018-05-13 Online:2018-09-20 Published:2018-09-30

Abstract:

In China, the prevalence of diabetes is increasing each year. Diabetic periodontitis, as a major complication of diabetes, retains a strong bidirectional correlation with diabetes. Periodontitis increases the risk of diabetes, and hyperglycemia aggravates periodontal inflammation. In recent years, efficient treatments for diabetic periodontitis have been increasingly emphasized, and the prevention and control of diabetic periodontitis remain difficult. It is very challenging to find the best way to recognize risk factors and increase the diagnosis rate. Deeply understanding the local and systematic biological features of diabetic periodontitis could lead to the development of clinical preventive and therapeutic strategies. This article reviews the clinical and biological characteristics of diabetic periodontitis and its treatment progress from a systemic and local perspective, with the aim of extending the work on the prevention and treatment strategies for diabetic periodontitis.

Key words: Periodontitis, Diabetes mellitus, Biological characteristics, Hyperglycemia, Advanced glycosylation end products, Interleukin-1β, Tumor necrosis factor-α, Prevention and treatment strategy

CLC Number: 

  • R781.4
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