Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (4): 205-211.DOI: 10.12016/j.issn.2096-1456.2019.04.001

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Current status of dental implantation therapy for diabetic patients

SONG Yingliang(),ZHANG Sijia   

  1. State Key Laboratory of Military Stomatology & National Clinical Research Center for Oral Diseases&Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Implant Dentistry, School of Stomatology, The Fourth Military Medical University, Xi’an 710032, China
  • Received:2018-10-31 Revised:2018-11-12 Online:2019-04-20 Published:2019-04-28
  • Contact: Yingliang SONG



  1. 军事口腔医学国家重点实验室,国家口腔疾病临床医学研究中心, 陕西省口腔生物工程技术研究中心,第四军医大学口腔医院种植科,陕西 西安(710032)
  • 通讯作者: 宋应亮
  • 作者简介:宋应亮,现任空军军医大学(第四军医大学)口腔医学院种植科教授、主任医师、博士生导师,中华口腔医学会口腔种植专业委员会与口腔激光专业委员会副主任委员。研究方向为临床种植与相关风险因素,以及激光技术在口腔种植中的应用。自2010年以来,带领课题组已在本领域内发表论文65篇,其中SCI论文23篇。主译口腔种植修复专著《种植修复学-临床操作指南》1部,参编《口腔种植学》全国高等学校研究生规划教材编写,另参编专著5部(1部为副主编)。获国家发明专利2项,实用新型专利6项。承担国家自然科学基金面上项目3项。
  • 基金资助:


In 2017, there were 451 million people (ages 18 to 99) with diabetes worldwide, and this number is expected to grow to 592 million by 2035. A series of complications in diabetic patients often leads to oral vascular and bone lesions. Therefore, dental implant doctors urgently need to understand the clinical characteristics of diabetes mellitus patients to provide the best treatment. For dental implant doctors, the following problems still exist in the treatment of diabetic patients with poor blood sugar control: ① alveolar fossa healing in diabetic patients is slow after extraction, and bone regeneration is often needed, which prolongs the treatment cycle and increases the pain of patients; ② the rate of new bone formation in diabetic patients after alveolar bone grafting is slow; ③ it takes a long time for the body to achieve effective bone bonding after dental implantation in diabetic patients, and the outcomes are poor; ④ the health of the tissue around dental implants is affected by blood sugar level, which is difficult to maintain in diabetic patients. Current studies suggest that the long-term success rate of implants is predictable in diabetic patients when blood sugar levels are well controlled (HbA1c < 6%). This article will review the current research status of dental implantation therapy for diabetic patients to provide a reference for clinical practice.

Key words: Oral implantation, Diabetes, Bone metabolism, Bone union, Implant success rate, Periimplant disease


2017年全世界有4.51亿(年龄18~99岁)糖尿病患者,预测至2035年这个数字将达5.92亿人,而糖尿病患者的一系列并发症常会导致其口腔相关的血管与骨组织病变,因此口腔种植科医生亟需了解糖尿病患者的临床特点以为其提供最佳的治疗方式。对于口腔种植医生而言,对血糖控制不良的糖尿病患者进行口腔种植治疗目前仍存在以下几项难题:① 糖尿病患者拔牙后牙槽窝愈合缓慢,常需辅以引导骨再生术,从而延长治疗周期,增加患者痛苦;② 糖尿病患者牙槽植骨后新骨生成率低;③ 糖尿病患者牙种植体取得有效骨结合所需时间长,效果差;④ 糖尿病患者牙种植体周围组织健康受血糖水平影响,维护不易。目前的研究认为,糖尿病患者当血糖水平得到很好控制时(HbA1c ≤ 6%),种植体的远期成功率是可预期的。本文将对糖尿病患者口腔种植治疗的研究现状进行述评,以期为临床提供参考。

关键词: 口腔种植, 糖尿病, 骨代谢, 骨结合, 种植体成功率, 种植体周围疾病

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