Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (7): 451-456.doi: 10.12016/j.issn.2096-1456.2019.07.008

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Apical sealability in extracted teeth by the root canal filling agents GuttaFlow and AH Plus: a systematic review

Xiyu YUAN1,Zhaoxia CONG1,Zeyu WU1,Jin ZHAO1,2()   

  1. 1.Department of Endodontics, The Affliated Stomatological Hospital of Xinjiang Medical University, Urumqi 830054, China
    2.Xinjiang Uygur Autonomous Region Institute of Stomatology, Urumqi , China
  • Received:2018-10-11 Revised:2019-03-05 Online:2019-07-20 Published:2019-07-24
  • Contact: Jin ZHAO E-mail:merryljin@sina.com

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Abstract:

Objective To compare the apical sealing effects of two root canal fillers, GuttaFlow and AH Plus, for clinical reference. Methods The Cochrane system evaluation method was used to search the Cochrane Library, Embase, CBM, PubMed, CNKI, Weipu, and Wanfang databases. Additionally, relevant journals and conference papers were manually retrieved, and relevant randomized controlled trials were collected. Two reviewers independently evaluated the quality of each study and extracted the data. A meta-analysis was performed using the RevMan5.3 software for homogenous studies, and a descriptive analysis was performed for studies with poor homogeneity. Results In total, 10 randomized controlled trials containing 398 isolated teeth were included. The meta-analysis results showed that the difference in apical microleakage was statistically significant at 1 week and 3 months [1 week: MD=-0.13, 95% CI (-0.22,-0.04), P=0.007; 3 months: MD=-1.27, 95% CI (-1.94,-0.60), P=0.000 2] but not at 6 months [MD=-0.10, 95% CI (-0.26, 0.06), P=0.23]. Conclusion Based on existing research results, GuttaFlow may achieve better results than AH Plus in the short term (≤ 1 week). Because it is subject to limitations of time, quality, and research methods, this conclusion requires more long-term, high-quality, large-sample, multimeasurement randomized controlled trials for further validation.

Key words: GuttaFlow, AH Plus, root canal therapy, root canal filling, microleakage, Meta-analysis

CLC Number: 

  • R781.05

Figure 1

Document retrieval process"

Table 1

Basic characteristics of the included studies"

纳入研究 研究类型 研究对象 样本数量（T/C） 干预措施 渗透时间 结局指标
T C
陈红 2015[5] RCT 离体单根管前牙 20/20 GuttaFlow AH plus 1周 ①
玛丽亚木古丽 2018[6] RCT 离体单根管前牙 20/20 GuttaFlow AH plus 1周 ①②
王茵 2015[7] RCT 离体单根管前牙 20/20 GuttaFlow AH plus 1周 ①③
吴林芮 2017[8] RCT 离体单根管恒牙 15/15 GuttaFlow AH plus 1周 ①
王小燕 2009[9] RCT 离体单根管前牙 20/20 GuttaFlow AH plus 1周 ②
周秀娟 2010[10] RCT 离体上、下颌前磨牙 19/19 GuttaFlow AH plus 无 ④
Patil P 2016[11] RCT 离体单根管前磨牙 20/20 GuttaFlow AH plus 悬浮72 h ①
Padmanabhan P 2017[12] RCT 离体下颌第一前磨牙 15/15 GuttaFlow AH plus 离心3 min ①
Anantula K 2011[13] RCT 离体单根管恒牙 20/20 GuttaFlow AH plus 无 ④
Elayouti A 2005[14] RCT 离体恒牙 30/30 GuttaFlow AH plus 无 ④

Table 2

Bias risk assessment of the included studies"

纳入研究 随机分配方法 隐蔽分组 盲法 结果数据的完整性 选择性报告 其他偏倚来源
陈红 2015[5] 不明确 不清楚 否 是 否 不清楚
玛丽亚木古丽 2018[6] 不明确 无 否 是 否 不清楚
王茵 2015[7] 不明确 不清楚 否 是 否 不清楚
吴林芮 2017[8] 不明确 不清楚 否 是 否 不清楚
王小燕 2009[9] 随机数字表 不清楚 否 是 否 不清楚
周秀娟 2010[10] 随机数字表 不清楚 否 是 否 不清楚
Patil P 2016[11] 不明确 不清楚 否 是 否 不清楚
Padmanabhan P 2017[12] 不明确 不清楚 否 是 否 不清楚
Anantula K 2011[13] 不明确 不清楚 否 是 否 不清楚
Elayouti A 2005[14] 不明确 不清楚 否 是 否 不清楚

Figure 2

Comparison of apical microleakage values at 1 week after root canal filling in the GuttaFlow and AH Plus groups"

Figure 3

Comparison of apical microleakage values at 3 months after root canal filling in the GuttaFlow and AH Plus groups"

Figure 4

Comparison of apical microleakage values at 6 months after root canal filling in the GuttaFlow and AH Plus groups"

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