Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (7): 457-463.DOI: 10.12016/j.issn.2096-1456.2019.07.009

• Cinical Study • Previous Articles     Next Articles

The oral health status of senile dementia patients: a systematic review

Peng ZHOU1,Jianping TAN2,Dan WANG1,Ming TANG1()   

  1. 1.Department of Stomatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
    2.Department of Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2018-12-22 Revised:2019-03-27 Online:2019-07-20 Published:2019-07-24
  • Contact: Ming TANG

老年痴呆患者口腔健康状况的系统评价

周鹏1,谭建苹2,王丹1,唐明1()   

  1. 1.重庆医科大学附属第一医院口腔科,重庆(400016)
    2.重庆医科大学附属第一医院颌面外科,重庆 (400016)
  • 通讯作者: 唐明
  • 作者简介:周鹏,医师,在读硕士研究生,Email: 673523758@qq.com

Abstract:

Objective To systematically evaluate the oral health status of senile dementia patients. Methods The CNKI, Wanfang, CBM, PubMed, Embase and Web of Science databases were searched online. Literature on the oral health status of Alzheimer′s patients published at home and abroad was collected. The search period extended to December 2018. Revman 5.3 software was used to perform the meta-analysis of homogeneous research. Results Ten studies satisfied the eligibility criteria. The meta-analysis revealed that older people with dementia had fewer remaining natural teeth [MD=-3.22 (95% CI -5.59, -0.85)] and more decayed missing filled teeth [MD=3.36 (95% CI 0.80, 5.92)] than the healthy control group (P < 0.05). The plaque index [MD=0.86 (95% CI 0.45, 1.28)], percentage bleeding on probing [MD=16.60 (95% CI 9.81, 23.39)], probing depth [MD=0.68 (95% CI 0.03, 1.34)], and clinical attachment loss [MD=1.13 (95% CI 0.38, 1.88)] were significantly higher in older people with dementia than in the healthy control group (P < 0.05). Conclusion The dental and periodontal health status of Alzheimer′s patients is worse than that of healthy controls. Thus, the former group needs special oral care and treatment.

Key words: dementia, older people, Alzheimer′s disease, oral health, periodontal disease, caries, Meta-analysis

摘要:

目的 对老年痴呆患者的口腔健康状况进行系统评价。方法 计算机检索CNKI、万方数据库、CBM、PubMed、EmBase、Web of Science数据库,收集国内外公开发表的研究老年痴呆患者口腔健康状况的观察性研究文献,检索时间截止至2018年12月。由2名研究者根据纳入与排除标准对相关文献进行筛选、质量评价和数据提取,对同质研究采用Revman 5.3软件进行Meta分析。结果 最终纳入10个研究,Meta分析结果显示与对照组人群相比,老年痴呆患者龋失补牙数多[MD=3.36,95% CI(0.80,5.92)],而剩余天然牙数少[MD=-3.22,95% CI(-5.59,-0.85)];老年痴呆患者的菌斑指数[MD=0.86,95% CI(0.45,1.28)]、探诊出血阳性百分比[MD=16.60,95% CI(9.81,23.39)]、探诊深度[MD=0.68,95% CI(0.03,1.34)]及附着丧失[MD=1.13,95% CI(0.38,1.88)]均要高于健康对照组,所有参数差异均有统计学意义(P < 0.05)。结论 老年痴呆患者牙体和牙周健康状况较健康对照人群差,需对这一人群进行特别的口腔护理和治疗。

关键词: 痴呆, 老年人, 阿尔茨海默病, 口腔健康, 牙周病, 龋病, Meta分析

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