Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (7): 457-463.doi: 10.12016/j.issn.2096-1456.2019.07.009

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The oral health status of senile dementia patients: a systematic review

Peng ZHOU1,Jianping TAN2,Dan WANG1,Ming TANG1()   

  1. 1.Department of Stomatology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
    2.Department of Maxillofacial Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China
  • Received:2018-12-22 Revised:2019-03-27 Online:2019-07-20 Published:2019-07-24
  • Contact: Ming TANG E-mail:1468492690@qq.com

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Abstract:

Objective To systematically evaluate the oral health status of senile dementia patients. Methods The CNKI, Wanfang, CBM, PubMed, Embase and Web of Science databases were searched online. Literature on the oral health status of Alzheimer′s patients published at home and abroad was collected. The search period extended to December 2018. Revman 5.3 software was used to perform the meta-analysis of homogeneous research. Results Ten studies satisfied the eligibility criteria. The meta-analysis revealed that older people with dementia had fewer remaining natural teeth [MD=-3.22 (95% CI -5.59, -0.85)] and more decayed missing filled teeth [MD=3.36 (95% CI 0.80, 5.92)] than the healthy control group (P < 0.05). The plaque index [MD=0.86 (95% CI 0.45, 1.28)], percentage bleeding on probing [MD=16.60 (95% CI 9.81, 23.39)], probing depth [MD=0.68 (95% CI 0.03, 1.34)], and clinical attachment loss [MD=1.13 (95% CI 0.38, 1.88)] were significantly higher in older people with dementia than in the healthy control group (P < 0.05). Conclusion The dental and periodontal health status of Alzheimer′s patients is worse than that of healthy controls. Thus, the former group needs special oral care and treatment.

Key words: dementia, older people, Alzheimer′s disease, oral health, periodontal disease, caries, Meta-analysis

CLC Number: 

  • R781

Figure 1

Flow diagram of the study identification and selection process"

Table 1

Basic characteristics of the included studies"

作者 年 国家 研究类型 样本量(女/男) 年龄(岁) 结局指标
痴呆组 对照组 痴呆组 对照组
Chu CH[8] 2015 中国 病例对照研究 27/12 59 79.8 ± 7.4 ≥60 DMFT、CPI
Aragón F[14] 2018 西班牙 病例对照研究 38/32 23/13 77.4 ± 10.6 62.6 ± 7.1 DMFT、CPI、RNT
D'Alessandro G[15] 2018 意大利 病例对照研究 83/37 60/43 79.1 77.68 RNT、CPI、GI
Ferreira RC[16] 2014 巴西 横断面研究 131 501 65~74 65~74 DMFT、CPI、CAL
Gil-Montoya JA[3,17] 2015 2017 西班牙 病例对照研究 240 324 78.25 ± 7.6 79.8 ± 8.3 PD、CAL、BOP%、PI、RNT
Lee KH[18] 2013 美国 横断面研究 40/17 60/109 81.7 ± 6.9 77.4 ± 5.8 PI、PD
Martande SS[19] 2014 印度 横断面研究 32/26 34/26 67.2 ± 7.3 64.5 ± 9.4 PI、GI、PD、CAL、BOP%
Zenth?fer A[20,21] 2017 2015 德国 队列研究 89/47 61/22 84.6 ± 8.1 87.0 ± 9.8 BOP%、PCR、DHI、CPI、RNT
热依拉·居热提[22] 2016 中国 横断面研究 62 63 65.2 ± 7.3 64.5 ± 9.4 PI、GI、PD、CAL、BOP、RNT
Cestari JAF[23] 2016 巴西 病例对照研究 28/16 14/7 75.71 ± 6.70 75.33 ± 5.75 PD、CAL、PCR、BOP%

Table 2

Quality evaluation of case-control studies in the included studies"

研究 A B C D E F G H I 总分
Chu CH 2015[8] 0 1 0 1 1 1 1 1 0 6
Aragón F 2018[14] 1 1 1 0 1 1 1 1 1 8
D′Alessandro G 2018[15] 0 1 0 1 1 1 1 1 0 6
Gil-Montoya JA 2017[3,17] 1 1 1 1 1 1 1 1 1 9
Cestari JAF 2016[23] 1 0 1 1 1 1 1 1 1 8

Table 3

Quality evaluation of cross-sectional studies and cohort studies in the included studies"

研究 a b c d e f g h i j k 总分
Ferreira RC 2014[16] 1 1 1 1 1 1 1 0 0 0 1 8
Lee KH 2013[18] 1 1 0 1 1 1 0 1 0 1 0 7
Martande SS 2014[19] 1 1 1 1 1 1 0 1 0 0 1 8
Zenth?fer A 2017[20,21] 1 1 1 1 0 1 1 1 0 0 1 8
热依拉·居热提 2016[22] 1 1 1 1 1 1 0 1 0 0 1 8

Figure 2

Comparison of decayed missing filled teeth between the dementia groups and control groups"

Figure 3

Comparison of remaining natural teeth between the dementia and control groups"

Figure 4

Comparison of plaque index between the dementia and control groups"

Figure 5

Comparison of percentage bleeding on probing between the dementia and control groups"

Figure 6

Comparison of probing depth between the dementia and control groups"

Figure 7

Comparison of clinical attachment loss between dementia groups and control groups"

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