Journal of Prevention and Treatment for Stomatological Diseases ›› 2020, Vol. 28 ›› Issue (8): 510-513.DOI: 10.12016/j.issn.2096-1456.2020.08.006

• Cinical Study • Previous Articles     Next Articles

Clinical report of cheek mass after injection and filling of hyaluronic acid in the cheek

LI Ming1,YAN Xingquan2,NAN Xinrong1,2()   

  1. 1. School of Stomatology, Shanxi Medical University, Taiyuan 030001, China
    2. Department of Stomatology, The First Hospital, Shanxi Medical University, Taiyuan 030001, China
  • Received:2019-10-30 Revised:2020-04-13 Online:2020-08-20 Published:2020-07-15
  • Contact: Xinrong NAN



  1. 1.山西医科大学口腔医学院,山西 太原(030001)
    2.山西医科大学第一医院口腔科,山西 太原(030001)
  • 通讯作者: 南欣荣
  • 作者简介:李明,硕士研究生在读,Email:
  • 基金资助:


Objective To investigate the clinical characteristics, differential diagnosis and treatment of cheek mass caused by hyaluronic acid injection. Methods From March 2014 to December 2018, data from 5 patients with cheek masses caused by cosmetic fillings admitted to the First Hospital of Shanxi Medical University were collected, and their clinical, imaging, surgical and pathological features were summarized. Results All 5 patients were young females with a history of facial hyaluronic acid filling injection. Their clinical features were buccal and facial nodular masses, all of which were treated with surgery. The pathological report was fibrous adipose tissue with fat necrosis, and chronic inflammatory cell infiltration was observed in the interstitium. After the operation, the face shape was basically symmetrical, and there were no symptoms such as infection, limited mouth opening or facial paralysis. Conclusion The injection of facial hyaluronic acid may cause complications of nodular masses in the cheek, and intraoral resection is an effective treatment with good prognosis.

Key words: hyaluronic acid, filling injection, complications, cheek mass, fibrous adipose tissue, fat necrosis, chronic inflammatory


目的 探讨透明质酸充填注射后致面颊部肿物的临床特点、鉴别诊断及防治措施。方法 收集2014年3月~2018年12月山西医科大学第一医院收治的5例因充填美容后引起面颊部肿物的患者,对其临床表现、影像学表现、外科手术及病理特点进行总结。结果 5例患者均为年轻女性,均有面部透明质酸充填注射史,其临床特点为面颊部结节性肿物,肿物均行外科手术治疗,病理报告为纤维脂肪组织伴脂肪坏死,间质内可见炎症细胞浸润。术后面型基本对称,无感染、张口受限及面瘫等症状,无需二次充填治疗。结论 面部透明质酸充填注射可能引发面颊部结节性肿物并发症,口内手术切除是其有效治疗措施,预后良好。

关键词: 透明质酸, 充填注射, 并发症, 面颊部肿物, 纤维脂肪组织, 脂肪坏死, 慢性炎症

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