Journal of Prevention and Treatment for Stomatological Diseases ›› 2020, Vol. 28 ›› Issue (8): 540-544.doi: 10.12016/j.issn.2096-1456.2020.08.012

• Review Articles • Previous Articles    

Progress in the application of metal and metal oxide nanoparticles in the antibacterial modification of dental materials

WANG Wanrong1,GU Junting1,GAO Peng2,LI Jing1,WAN Meichen1,JIAO Kai1,NIU Lina1()   

  1. 1. State Key Laboratory of Military Stomatology, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Oral Diseases, School of Stomatology, Department of Prosthodontics, The Fourth Military Medical University, Xi′an 710049, China
    2. Department of Stomatology, Third Affiliated Hospital of Xinxiang Medical College, Xinxiang 453003, China
  • Received:2019-11-08 Revised:2020-04-11 Online:2020-08-20 Published:2020-07-15
  • Contact: Lina NIU E-mail:niulina831013@126.com

Abstract:

The colonization of microorganisms planted on the surface of teeth and restoration materials is the main cause of oral disease and treatment failure. How to improve the antibacterial properties of dental materials is a hot topic in dentistry. Nano-sized antibacterial materials have attracted much attention. Among them, metal and metal oxide nanoparticles are prominent due to their strong and broad-spectrum antibacterial activity. Thus, in recent years, many studies have used metal and metal oxide nanoparticles to develop antimicrobial dental materials for resin restoration, root canal therapy, orthodontic treatment, and implant surface and removable denture repair and have found that the antibacterial properties of nano-sized materials are significantly enhanced. However, the mechanical properties and esthetic properties of the modified materials are affected, so it is still necessary to explore appropriate modification methods. In addition, most of the experiments are carried out in vitro, which cannot accurately simulate the oral environment. Therefore, the antibacterial effect, cytotoxicity and immune response of these materials in vivo still need further research and exploration. This paper reviewed the potential antibacterial mechanisms and the safety of those nanoparticles and their applications in dentistry.

Key words: metal, metal oxide, nanoparticles, microorganism, antibacterial modification, dental materials, safety, cytotoxicity, immune response

CLC Number: 

  • R783.1
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