Journal of Prevention and Treatment for Stomatological Diseases ›› 2021, Vol. 29 ›› Issue (2): 135-139.DOI: 10.12016/j.issn.2096-1456.2021.02.012

• Review Articles • Previous Articles     Next Articles

Research progress on autologous fat transplantation in the treatment of velopharyngeal insufficiency

LU Lidan1(),XU Hui2()   

  1. 1. Postgraduate college of Xinjiang Medical University, Urumqi 830011, China
    2. Department of Oral and Maxillofacial Surgery, People′s Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830011, China
  • Received:2020-04-14 Revised:2020-09-02 Online:2021-02-20 Published:2020-12-21
  • Contact: Hui XU
  • Supported by:
    grants from Natural Science Foundation of Xinjiang Uygur Autonomous Region(2015211C203)



  1. 1.新疆医科大学研究生院,新疆维吾尔自治区 乌鲁木齐(830011)
    2.新疆维吾尔自治区人民医院口腔颌面外科,新疆维吾尔自治区 乌鲁木齐(830011)
  • 通讯作者: 许辉
  • 作者简介:路利丹,硕士研究生在读,Email:
  • 基金资助:


Autologous fat transplantation in the treatment of velopharyngeal insufficiency has the advantages of good histocompatibility, small local trauma, few complications, reversible operation and simple postoperative nursing, which can effectively increase the velopharyngeal closure area. If the clinical effect is poor, other surgical methods can be used at any time for replacement. Although there are many advantages in the treatment of velopharyngeal insufficiency with autologous fat transplantation, there are still some problems in the selection of indication, donor site, injection dose, recipient site, follow-up evaluation, complications and prevention and treatment. Current research shows that autologous fat transplantation is mainly used in patients with mild or moderate velopharyngeal insufficiency, but with the improvement of fat acquisition and treatment techniques, the indications for autologous fat transplantation continue to expand, and autologous fat transplantation combined with palatoplasty or pharyngoplasty has been proposed for the treatment of severe velopharyngeal insufficiency. However, there are complications, such as fat absorption and obstructive sleep apnea syndrome. In addition, the application of autologous fat transplantation in severe VPI patients and how to improve the long-term stability of autologous fat transplantation need further study.

Key words: autologous fat transplantation, velopharyngeal insufficiency, cleft palate, autologous fat transplantation, indications, donor site, velopharyngeal insufficiency, cleft palate, injection dose, recipient site, indications, complications, donor site, injection dose, recipient site, complications



关键词: 腭裂, 适应证, 自体脂肪移植, 腭咽闭合不全, 供区部位, 腭裂, 注射剂量, 适应证, 受区部位, 供区部位, 并发症, 注射剂量, 受区部位, 并发症

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