Journal of Prevention and Treatment for Stomatological Diseases ›› 2021, Vol. 29 ›› Issue (5): 322-327.DOI: 10.12016/j.issn.2096-1456.2021.05.005

• Clinical Study • Previous Articles     Next Articles

Accuracy analysis of MRI in the depth of invasion assessment of tongue squamous cell carcinoma

LI Ming1(),NAN Xinrong2,YUAN Zhenying2,TANG Zhangui1   

  1. 1. Xiangya Stomatological Hospital, Central South University, Changsha 410000, China
    2. Department of Stomatology, First Hospital of Shanxi Medical University, Taiyuan 030001, China
  • Received:2020-10-18 Revised:2020-12-01 Online:2021-05-20 Published:2021-03-08
  • Contact: Ming LI
  • Supported by:
    National Natural Science Foundation of China(8167041124)

磁共振成像评估舌鳞状细胞癌浸润深度的准确性分析

李明1(),南欣荣2,原振英2,唐瞻贵1   

  1. 1.中南大学湘雅口腔医院,湖南 长沙(410000)
    2.山西医科大学第一医院口腔科,山西 太原(030001)
  • 通讯作者: 李明
  • 基金资助:
    国家自然科学基金项目(8167041124)

Abstract:

Objective To analyze the accuracy of the infiltrating depth of tongue squamous cell carcinoma measured by magnetic resonance imaging (MRI) using pathological sections under a light microscope to provide a clinical reference. Methods Seventy-three patients with tongue squamous cell carcinoma who visited the Department of Stomatology of the First Hospital of Shanxi Medical University and Xiangya Stomatological Hospital from January 2018 to September 2020 were selected. Preoperative MRI was performed to evaluate the infiltration depth of tongue squamous cell carcinoma, and intraoperative frozen pathological sections were used to confirm the infiltration depth of tongue squamous cell carcinoma measurement. Results The infiltration depth of tongue squamous cell carcinoma measured by T1-weighted imaging was 1.11 mm (95% CI=0.51-1.70; t=3.72; P < 0.001), and the correlation coefficient r was 0.95. The T2-weighted average overestimation was 2.17 mm (95% CI=1.32-3.02; t=5.10; P < 0.001), and the correlation coefficient was 0.92. The Bland-Altman plot showed good consistency between T1- and T2-weighted images and pathologic measurements. Conclusion The infiltration depth of tongue squamous cell carcinoma measured by MRI is more accurate, with an average overestimation of 1-2 mm compared with pathological measurements, and T1-weighted images are better than T2-weighted images.

Key words: squamous cell carcinoma, tongue squamous cell carcinoma, oral squamous cell carcinoma, oral cancer, tongue neoplasms, depth of invasion, magnetic resonance imaging, pathological examination

摘要:

目的 以光镜下病理切片为参照,分析磁共振成像(magnetic resonance imaging,MRI)测量的舌鳞状细胞癌浸润深度的准确性,为临床提供参考。方法 选取2018年1月至2020年9月就诊于山西医科大学第一医院口腔科和中南大学湘雅口腔医院的73例舌鳞状细胞癌患者,术前均行MRI评估舌鳞状细胞癌浸润深度,术中冰冻病理切片再次测量舌鳞状细胞癌浸润深度。结果 T1加权成像测量的舌鳞状细胞癌浸润深度较病理结果平均高估1.11 mm (95%CI=0.51~1.70,t=3.72,P<0.001),相关系数r为0.95;T2加权像平均高估2.17 mm (95%CI=1.32~3.02,t=5.10,P<0.001),相关系数r为0.92。Bland-Altman图显示T1、T2加权像与病理测量的浸润深度一致性佳。结论 MRI测量的舌鳞状细胞癌浸润深度较为准确,与病理测量结果相比有平均1~2 mm的高估,其中T1加权像优于T2加权像。

关键词: 鳞状细胞癌, 舌鳞状细胞癌, 口腔鳞状细胞癌, 口腔癌, 舌肿瘤, 浸润深度, 磁共振成像, 病理检查

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