Journal of Prevention and Treatment for Stomatological Diseases ›› 2020, Vol. 28 ›› Issue (2): 102-106.DOI: 10.12016/j.issn.2096-1456.2020.02.008

• Review Articles • Previous Articles     Next Articles

Research progress on factors affecting bacterial adhesion on the oral implant surface

ZHOU Wen1,2,PENG Xian1,CHENG Lei1,2()   

  1. 1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, Chengdu 610041, China
    2. Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2018-11-22 Revised:2019-09-24 Online:2020-02-20 Published:2020-02-25
  • Contact: Lei CHENG



  1. 1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心,四川 成都(610041)
    2. 四川大学华西口腔医院牙体牙髓病科,四川 成都(610041)
  • 通讯作者: 程磊
  • 作者简介:周雯,博士研究生在读,Email:
  • 基金资助:


Reducing the adhesion of microorganisms and the formation of biofilms on implant surfaces can prevent peri-implant inflammation and optimize the long-term prognosis of implanted dentures. To provide theoretical support for the development of new materials or the modification of existing materials and the improvement of the success rate of implant repair, a literature review was conducted, which shows that the factors influencing bacterial adhesion on dental implant surfaces included the type of implant material, material roughness, nonspecific physical and chemical properties, the type of antibacterial coating, the components of the acquired membrane on the implant surface, the structure of the bacterial cell wall, etc. The current research direction of implant materials aims to reduce bacterial adhesion and promote bone bonding. However, there is no consensus on the physical and chemical properties of implants that meet this requirement. At present, the development trend in implant materials is guided by research of the “core microbiome” of peri-implant inflammation, based on study of the factors related to the adhesion of pathogenic microorganisms to the implant surface, which is organically combined with a variety of modification methods to change the surface-related properties of the implant materials and even to endow the implant with antibacterial properties to reduce or inhibit the adhesion of pathogenic bacteria to the implant.

Key words: dental implant materials, bacterial adhesion, surface properties, surface modification, physical-chemical properties, antibacterial coating, acquired layer, cell wall, biofilm, peri-implant inflammation, core microbiome



关键词: 牙种植体材料, 细菌黏附, 表面特性, 表面改性, 理化性质, 抗菌涂层, 获得性膜, 细胞壁, 生物膜, 种植体周围炎, 核心微生物组

CLC Number: