Journal of Prevention and Treatment for Stomatological Diseases ›› 2019, Vol. 27 ›› Issue (4): 231-235.doi: 10.12016/j.issn.2096-1456.2019.04.005

• Basic Study • Previous Articles     Next Articles

Remineralization effect of nanohydroxyapatite on adjacent glazed surfaces

HU Beibei,BAI Hai,JIA Wanping,LIANG Yongqiang()   

  1. Department of Orthodontics, College of Stomatology, North China University of Science and Technology, Tangshan 063000, China
  • Received:2018-09-25 Revised:2018-11-09 Online:2019-04-20 Published:2019-04-28
  • Contact: Yongqiang LIANG


Objective To investigate the effect of a nanohydroxyapatite suspension with a 10% mass fraction on enamel demineralization after adjacent enamel removal and to provide a reference for the clinical use of nanohydroxyapatite to prevent enamel demineralization after adjacent enamel removal. Methods Forty fresh extracted premolars were incised from the coronal surface of the crown after glazing and polishing with sand strips. Each tooth was made into two specimens. Eighty teeth were randomly divided into four groups: a blank group, a dolofluoride group, a dental mousse group and a 10% nanohydroxyapatite group. After 30 days of pH cycling in vitro, a microhardness tester was used to detect the enamel surface elements before and after deglazing treatment. Scanning electron microscopy (SEM) and X-ray energy dispersive spectrometry (EDS) were used to analyze the enamel surface elements. Results After the experiment, the microhardness values of the adjacent glazed specimens of the four groups were (128.18 ± 6.89) kg/mm2 in the blank group, (216.75 ±9.87) kg/mm2 in the dolefluoride group, (198.88 ± 4.76) kg/mm2 in the dental care group and (218.44 ± 7.88) kg/mm2 in the 10% nanohydroxyapatite group, which were significantly different (F=189.14, P< 0.001). The LSD-t test showed that there was no significant difference between the dolefluoride group and the 10% nanohydroxyapatite group (P< 0.05), but the differences between the other groups were statistically significant (P > 0.05). There were significant differences in the Ca/P ratio among the blank group (1.39 ± 0.08), the dolefluoride group (1.70 ± 0.11), the dental care group (1.54 ± 0.12) and the 10% nanohydroxyapatite group (1.71 ± 0.14) (F=10.539, P< 0.001). There was no significant difference between the dolefluoride group and the nanohydroxyapatite group after the experiment (P > 0.05), but there were significant differences among the other groups (P< 0.05). Conclusion Dolerofluoride, dental protector and 10% nanohydroxyapatite can promote remineralization of enamel after enamel removal. The remineralization induced by 10% nanohydroxyapatite is similar to that induced by dolerofluoride.

Key words: Nanohydroxyapatite, Dorafluoride, Dental Mousse, Adjacent Deglazing, Demineralization, Remineralization, Microhardness

CLC Number: 

  • R783

Table 1

The SMH values in each group n = 10,kg/mm2,$\bar{x}$ ± s"

组别 MH0 MH1 t P
A 295.05 ± 7.04 128.18 ± 6.89 85.804 <0.001
B 297.23 ± 6.24 216.75 ± 9.87 18.736 <0.001
C 298.39 ± 8.69 198.88 ± 4.76 30.715 <0.001
D 296.18 ± 6.91 218.44 ± 7.88 19.676 <0.001
F 0.23 189.14
P 0.874 <0.001

Figure 1

EDX analysis of each group"

Figure 2

The surface morphology of permanent enamel of 4 groups (SEM, × 2000)"

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