20 January 2016, Volume 24 Issue 1

    

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Expert Commentary
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  The application of distraction osteogenesis in the temporomandibular joint ankylosis and secondary dentofacial deformities

  ZHU Song-song, HU Jing

  journal1. 2016, 24(1): 6-10. https://doi.org/10.12016/j.issn.2096-1456.2016.01.001

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  Temporomandibular joint (TMJ) ankylosis is a joint disorder which refers to bone or fibrous adhesion of the anatomic joint components and the ensuing loss of function. When it occurs in children, it can cause secondary dentofacial deformities with physical and psychological disability. Correction of TMJ ankylosis and secondary deformities remains a great challenge for oral and maxillofacial surgeons. Distraction osteogenesis (DO) has been used for the treatment of TMJ ankylosis and secondary deformities with satisfactory outcomes. An average of 50-60 patients with TMJ ankylosis is referred to our department annually.In this review, we summarized the characteristics of DO and discussed some factors involved in the treatment of TMJ ankylosis with dentofacial deformities.
Expert Forum
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  The influence of the impacted mandibular third molar extraction on the distal periodontal tissue of the mandibular second molar

  XU Jing

  journal1. 2016, 24(1): 11-14. https://doi.org/10.12016/j.issn.2096-1456.2016.01.002

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  The periodontal bone defect might be formed on the distal surface of the second molar root followed the extraction of the mandibular third molar. The occurrence and prognosis of the complication would be influenced by the age of extraction, the impaction level of the third molar, local inflammation, health state of adjacent tooth, etc. The periodontal bone defect of the second molar would be severer and had poorer prognosis in the case of extraction for the older patients, deeper impaction of the third molar, local inflammation, food impaction, adjacent tooth caries. From the prophylactics, it was beneficial for the prevention of the complication or reducing severity of the complication when the extraction of lower third molar was performed before the age of 25 years old. The periodontal bone defect could be effectively repaired by transplanting bone graft.
Basic Study
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  Ion Torrent RNA-Seq detection and analysis of the long non-coding RNA in tongue squamous cell carcinoma

  OUYANG Ke-xiong1, LIANG Jun, ZOU Rui, LI Zhi-qiang, BAI Zhi-bao, PIAO Zheng-guo, ZHAO Jian-Jiang.

  journal1. 2016, 24(1): 15-19. https://doi.org/10.12016/j.issn.2096-1456.2016.01.003

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  Objective To study the difference of LncRNA expression profiles between tongue squamous cell carcinoma (TSCC) and the corresponding adjacent normal tissue. To explore the role of long non-coding RNA in gene regulation. Methods One fresh sample of TSCC tissue and the adjacent normal tongue tissue were selected. After extracting the total RNA, the LncRNA from different tissues was screened and compared by Ion Torrent RNA-Seq. Pick LncRNA read sequence by the method used Bowtie2, then calculate the reads per kilo bases per million reads, RPKM of LncRNA by the method then Cufflinks. Choose the RPKM ratio of LncRNA from Cancer and adjacent tissue as a candidate target. Results According to RNA-Seq, 52 LncRNA whose value of RPKM with a fold＞10 or ＜0.1 compared to the adjacent normal tongue tissue was enrolled in this study, of which 28 was up-regulated expression, 24 was down-regulated expression. Conclusion LncRNA expression profiles may be an important potential targets in TSCC.
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  The influence of the roughness of zirconia ceramic surface on microbial attachment

  YU Pei, XUE Jing, ZHANG Xiao-wei, ZHENG Cang-shang

  journal1. 2016, 24(1): 20-25. https://doi.org/10.12016/j.issn.2096-1456.2016.01.004

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  Objective To analyze the influence of the zirconia ceramic surface roughness on microbial attachment. Methods The surface of zirconia ceramics was abraded progressively into three roughness levels of rough, medium rough and smooth surface by silicon carbide sand papers. Then the surface roughness, surface morphology and contact angle of zirconia ceramic were measured by atomic force microscopy and optical contact angle measuring device, which was followed by detecting the adhesive force of different roughness of zirconia ceramic by Streptococcus mutans UA159 preprocessed probe. At last scanning electron microscope and confocal laser scanning microscopy were used to observe biofilm formation after co-culture of zirconia ceramics and Streptococcus mutans. Results For different roughness of zirconia ceramic surface, with the smoother degree of their surfaces, the contact angle decreases step by step, surface energy increases gradually, surface biofilm thickness decreases generally, and adhesive force between Streptococcus mutans and surface of zirconia ceramics decreases by degrees, whereas the biofilm bacteria mass of different roughness of zirconia ceramics does not have statistical difference. Conclusion Zirconia surface roughness affects the adhesion force of Streptococcus mutans which grows with the increase of surface roughness. The biofilm thickness and the mass of microorganisms lessened correspondingly with the decreasing of surface roughness, until it drops to a certain number, from where the biofilm thickness and the mass of microorganisms remains stable.
Clinical Study
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  The evaluation of Eagle syndrome treatment by surgery combined with antidepressant therapy

  ZHONG Jiang-long, PAN Ji-yang, CHEN Wei-liang

  journal1. 2016, 24(1): 26-28. https://doi.org/10.12016/j.issn.2096-1456.2016.01.005

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  Objective To evaluate the effect of Eagle syndrome treatment by styloid resection from extraoral approach combined with antidepressants therapy. Methods 32 patients with Eagle syndrome got a score over 49 in a self-rating depression scale preoperatively, and they were all diagnosed as depression. All patients underwent resection of the elongated styloid processes under general anesthesia via an extra-oral approach, furthermore 16 patients in the experiment group were treated with fluoxetine 20 mg/day for 3 weeks postoperatively, which was not used in the control group. Beside this, other treatment were all the same. They were all followed for 12-36 months for the comparation of their treatment effect. Results No surgical complications were observed. The cure rate in the experiment group is 93.8% whichin the control group is 68.8%. No complications occurred in any patient with depression medicine intervention. All patients had satisfactory cosmetic Results and no paresthesias. Conclusion Dissection of styloid process via an extra-oral approach is operationable and reliable, as depression is one of the main problems in patients with Eagle syndrome, dissection of styloid process combined with antidepressants (fluoxetine) is preferred for treating Eagle syndrome.
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  Clinical observation of sternocleidomastoid muscle flaps combined with artificial biological membrane reparing the defects after parotidectomy

  LU Jian-rong, BAN Hua-jie, WANG Dai-you, ZHOU Hui-hui, LONG Ru, QIN Shu-hua

  journal1. 2016, 24(1): 29-32. https://doi.org/10.12016/j.issn.2096-1456.2016.01.006

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  Objective To investigate therapeutic effects of sternocleidomastoid muscle flaps combined with artificial biological membrane in repairment of facial concave deformity and prevention of taste sweating syndrome after parotidectomy. Methods 68 cases of patients were randomly divided into two groups. The repair group, 36 cases, received the repair of partial sternocleidomastoid muscle flaps combined with artificial biological membrane, while the control group, 32 cases,had normal treatment without repairmen after parotidectomy. The two groups of patients were followed up for 6-18 months. The incidence of facial concave deformity and taste sweating syndrome were statistically compared and analyzed. Neck movements also were tested. Results The incidence rate of facial concave deformity was 8.33% (3/36) in the repair group and 81.25% (26/32) in the control group. Taste sweating syndrome occurred 5.56% (2/36) in the repair group and 62.50% (20/32) in the control group. Both the incidence rates between two groups had the significant difference(χ²=25.10, P＜0.05). Neither of each group had dysfunction of neck movement. Conclusion Sternocleidomastoid muscle flap combined with artificial biological membrane repairing the defects of post-parotidectomymay significantly improve facial concave deformity and prevent taste sweating syndrome.
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  The study of colorimetric board of porcelain fused to metal restoration for moderate to severe dental fluorosis

  CHEN Xi, SUN Qin-zhou

  journal1. 2016, 24(1): 33-36. https://doi.org/10.12016/j.issn.2096-1456.2016.01.007

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  Objective To study the colorimetric board of porcelain fused to metal (PFM) restorations for severe dental fluorosis. Methods 300 pieces of metal plates with different dyeing formulations of glazed ceramic powder were fabricated. The colorimetric parameter values of these colorimetric plates were determinate by Shade Eye-NCC (the 2nd generation computer colorimetric instrument), and the values were compared with fluorosis values of tooth-colored degrees. Results The colors of group B 4, 5 plate, group F 2, 4, 5 plate, and group G1 plate were clinically acceptable. Conclusion The metal-based colorimetric boards in this study might be a new method to make shade guide for fluorine spot teeth.
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  Lip soft tissue measurement and assessment on before and after orthodontic treatment of Class Ⅱ division 1 malocclusicn adults

  CAO Fang, WANG Zhen, YAN Lin, JIAO Lan, DAI Jing-tao, HUANG Xiao-wen

  journal1. 2016, 24(1): 37-39. https://doi.org/10.12016/j.issn.2096-1456.2016.01.008

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  Objective Lip soft tissue were measured and assessed before and after orthodontic treatment of Class Ⅱ division 1 adults in order to instruct the clinical work. Methods A total of 30 post-treatment adult patients of Class Ⅱ division 1 were selected, whose post-treatment model and cephalometric data were within the normal range. The pre- and post-treatment front image and lateral cephalograms lip sagittal thickness and vertical thickness measurement. Results Post-treatment upper lip vertical become thinner and lower lip vertical thickness is bigger which has a statistically significant gap. Upper lip vermilion of the initial tissue thickness after treatment increased, lower lip vermilion of initial tissue thickness had a tendency to decrease after treatment, and there was statistical significance. The retraction of upper incisor cervical point (U1C) was positively correlated with upper lip retraction (TUL). The retraction of lower incisor cervical point (L1C) was positively correlated with lower lip retraction (TLL). And the retraction of upper incisor most anterior point was positively correlated with lower lip retraction. Conclusion Upper and lower lip retraction in Class Ⅱ division 1 Chinese adults could be effectively predicted by the retraction of incisors after extraction orthodontic treatment.
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  Clinical analysis of pain after two kinds of apical stop preparation

  LI Bin, HE Xiao-ning, GAO Yuan, HU Yu-ping

  journal1. 2016, 24(1): 40-43. https://doi.org/10.12016/j.issn.2096-1456.2016.01.009

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  Objective To evaluate the effect of two different root canal therapy on postoperative pain of root canal preparation. Methods Patients need to do root canal treatment of 118 cases were randomly divided into two groups: group A (59), root canal working length of apical stop point located in the root tester instructions arc baseline on the highest point (Beep 35 times / min); group B (59), root canal working length of apical stop point located in the root tester instructions arc baseline nadir (Beep 65 times/min), pain visual simulation score (visual analogue scale, VAS) scores recorded root of two groups of patients with preoperative preparation and after 12 h, 1 d, 2 d, 3 d, 1 week pain situation tube. Results In 118 cases, the total incidence rate of tooth pain was 18.6%, the A group was 16.9%(10/59), and the B group was 20.3% (12/59), and there was no significant difference between 2 groups (P＞0.05 ). VAS of two groups had no statistical significance (P＞0.05 ). Conclusion There was no significant difference for postoperative pain of the two kinds of apical stop preparations.
Prevention and Treatment Practice
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  Clinical assessment of two fissure sealant techniques in children’s dental caries prevention

  LIU Fang

  journal1. 2016, 24(1): 44-45. https://doi.org/10.12016/j.issn.2096-1456.2016.01.010

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  Objective To compare clinical effects of children’s dental caries prevention with enameloplasty sealant technique (EST) and traditional fissure sealant technique. Methods 50 children with healthy teeth were selected randomly ,from the age of 6 to 8.5 years old and to tally 82 pairs of first molars were included (different sides of the same jaw was considered as a pair). In a self-control study, the right side was treated through enameloplasty sealant technique (group A), the left side was cured with traditional fissure sealant technique (group B). According to follow-up visit after 1 year, 2 years and 3 years, the Results of two sealant techniques were evaluated. Results The incidence of group A was 2.5%, 3.9%, 5.7% from 1-3 years, whereas the incidence of group B was 2.5%, 10.4% and 15.7%. No significant statistic difference was shown in the first year. However significant statistic difference was illustrated in the second and third year (P＜0.05). Conclusion For preventing dental caries in children, enameloplasty sealant technique showed a better long-term clinical effect.
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  Case report and literature review of nasopharyngeal carcinoma misdiagnosed as endodontic disease

  GUO Meng-zhu, LUO Zhi-jie, LIANG Jun-li, YU Da-hai, LI Jing

  journal1. 2016, 24(1): 46-48. https://doi.org/10.12016/j.issn.2096-1456.2016.01.011

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  The early symptom of nasopharyngeal carcinoma is not obvious, it is easy to be misdiagnosed as endodontic disease with the first symptom of headache in the department of stomatology. The authors report a case of nasopharyngeal carcinoma misdiagnosed as endodontic disease and discuss the causes of misdiagnosis,the differential diagnosis and preventive measures, which helps strengthen the understanding of this disease and reduce the occurrence of misdiagnosis.