Correction of bimaxillary deformities remains a great challenge for oral and maxillofacial surgeons. With the development of orthognathic surgery and orthodontic technique, especially the application of digital surgery, more and more advanced methods were used in the diagnosis and treatment for patients. Average of over 100 patients with bimaxillary deformities were referred to our department annually. Almost all the patients received satisfactory outcomes. In this review, we summarized and discussed some factors involved in the correction of bimaxillary deformities.
Objective To observe the clinical efficacy of multipoint radiofrequency thermal coagulation on trigeminal neuralgia management. Methods 180 patients diagnosed as primary trigeminal neuralgia were included in this study. The patients were randomly divided into three groups, 60 patients in treatment group, 60 patients in the first control group and 60 patients in second control group respectively. Multipoint radiofrequency ablation therapy was utilized in the treatment group, radiofrequency thermal coagulation therapy on trigeminal ganglion was applied in the first control group and patients in second control group were treated by nerve block therapy. Then the curative effect of the three groups after the treatment was compared and analyzed. Results To the curative effects, the VAS score showed insignificant difference between treatment group and the first control group (P>0.05), while an significant difference between treatment group and the second control group (P<0.05). To the complications concerned, higher occurrence was found in the first control group. There was no significant difference between the treatment group and the first control group in the recurrence rate (P>0.05). Conclusion The minimally invasive multipoint radiofrequency ablation on the treatment of trigeminal neuralgia has significant effect with fewer complications and higher patients safety.
Objective To investigate the efficiency of different concentrations of genipin and silk fibroin (SF)∶ chitosan (CS) ratios on the package and release of SF-CS composite microspheres. Methods Selected the microspheres with a SF∶CS ratio of 1∶1 to encapsulate different concentrations of bovine serum albumin (BSA) and compared their encapsulation efficiency and sustained-release rate with those of pure chitosan microspheres. SF-CS microspheres were prepared with emulsion cross-linking technique. The microspheres were observed by scanning electron microscope. Size distribution was measured by a laser particle size analyzer. X-ray diffractometry (XRD), fourier transform infrared spectroscopy (FTIR) and thermogravimetricanalyzer (TGA) were used to analyze their structural characteristics. BCA method was used for determination of the drug entrapment, loading rate and cumulative release of the total drug. Results The five types of microspheres (m (CS): m (SF) = 1∶0.5, 0.1 g or 0.5 g genipin; m (CS)∶m (SF) = 1∶1, 0.05 g or 1 g genipin; m (CS)∶m (SF) = 1∶2, 0.5 g eniping) had a more spherical shape and smooth surface with particle size between 70-147 μm. The microspheres prepared with m (CS)∶m (SF) of 1∶1 and 0.05 g genipin in the presence of 10 mg,20 mg, or 50 mg BSA of BSA burst-released (30.79±3.43)%, (34.41±4.46)%, or (41.75±0.96)% of the entrapped BSA on the first day, and cumulatively released (75.20±2.52)%, (79.16±4.31)%, and (89.04±4.68)% in 21 d, respectively. The pure CS microspheres prepared in the presence of 10 mg BSA burst-released (39.53±1.76)% on the first day and cumulatively released (83.57±2.33)% of the total encapsulated BSA in 21 d. Conclusion The SF-CS composite microspheres had a higher sustained release rate than the pure CS microspheres and may be a better drug carrier.
Objective To study the matching of dental and basal bone arch form in three-dimensional space in individual normal occlusion, to provide references for the clinical treatment. Methods A total of 30 subjects with individual normal occlusion were selected and taken CBCT, the dental arch and the basal bone arch mark point coordinates were processed by mathematical method in order to establish the matching mathematical equation of maxilla and mandibular, the matching mathematical equation of the dental arch and basal bone arch by statistical analysis. Results The width and depth of maxilla and mandibular dental arch were highly correlated in canine region and the second molar region. The width and depth of basal bone arch were moderate correlated in canine region,and strong correlated in the second molar region. Conclusion Maxilla and mandibular dental arch, the basal bone arch of individual normal occlusion were highly correlated in the width and depth of canine region and the second molar region. Personalized dental arch matching mathematical equation was established through the regression equation.
Objective To investigate the correlation of Helicobacter pylori infection in the oral cavity and stomach, and correlation of Helicobacter pylori infection in the oral cavity and periodontitis. Methods 120 patients with chronic gastric diseases received 13C-urea breath test, Hp saliva test and periodontal examination. The correlation of Helicobacter pylori infection in the oral cavity and stomach, and correlation of Helicobacter pylori infection in the oral cavity and periodontitis were analyzed. Results The experiments showed that the positive rate of Hp in the oral cavity was 87.7% in stomach-Hp-positive patients, while the positive rate of Hp in the oral cavity was only 42.6% in stomach-Hp-negative patients, which was significantly lower (P<0.001). The positive rate of Hp in the oral cavity in patients with normal periodontium, mild periodontitis, moderate periodontitis and severe periodontitis were 45.5%, 55.3%, 81.5% and 82.4% separately, and the difference was statistically significant (P<0.01). Conclusion Hp infection in the oral cavity is closely related to its infection in the stomach, and is also related to the severity of periodontitis.
Objective To investigate the perpendicular occlusal condition of the mesially impacted mandibular third molars and its relationship with temporomandibular joint disorders (TMD). Methods Thirty-seven cases of mesially impacted mandibular wisdom teeth were selected as the observation group, and 20 cases of other oral diseases without the mesially impacted third molars were selected as the control group from Jun 2012 to Sep 2014. Occlusion in the vertical, buccal-lingual and mesial-distal directions were analyzed with occlusion index.Depth of Spee curve was measured by AutoCAD software. Results Prevalence of TMD of observation group (51.4%) was significantly higher than the control group (15.0%), the difference between the two groups was statistically significant (χ 2=7.24, P=0.007). Observation group's vertical abnormal occlusion rate (40.5%) was significantly higher than the control group (10.0%), the difference between the two groups was statistically significant (P<0.05). Average depth of Spee curve in observation group and control group were (2.41±0.26) mm and (2.05±0.18) mm respectively, the difference was statistically significant (t=4.51, P=0.009). Conclusion Incidence of TMD in patients with mesially impacted mandibular wisdom tooth is higher than that of patients without mesially impacted mandibular wisdom tooth. Mandibular impacted wisdom tooth may cause vertical abnormal occlusion. TMD is related to vertical abnormal occlusion.
Objective To explore the reliability of liquid nitrogen cryotherapy for infant lip mucosa venous malformations.Methods A retrospective review of 57 pediatric patients with venous malformations involving the lips who underwent liquid nitrogen cryotherapy was enrolled in. Among them, 35 patients were males and 22 patients were females; the age of the patients ranged from 3 to 21 months (average 7.4 months). Photographs were taken preoperatively, immediately postoperatively and one month postoperatively. Following up period was 2-16 months and the outcome was assessed.Results 71.9% cases were completely effective, 19.3% cases were mostly effective, 8.8% cases were partially effective. No cases showed the anesthesia complications.Conclusion Liquid nitrogen cryotherapy is an effective, simple and safe treatment for lip mucous venous malformations.
Objective To investigate the efficacy of carbon-nanoparticles suspension in detecting sentinel lymph nodes in cT1-2N0 oral tongue carcinoma and explore the application value of carbon-nanoparticles suspension in sentinel lymph node biopsy. Methods Fifty-eight patients with cT1-2N0 oral tongue carcinoma were enrolled in this prospective trial. Thirty patients received carbon nanoparticle injection around the tumor pre-operatively (experimental group), and the remaining 28 were injected with methylene blue dye (control group). All patients underwent elective neck dissection and routine pathological examination was performed in all resected specimens. Results The experimental group had a clear surgical field compared with the control group, and there is clear boundary between the staining lymph nodes and surrounding tissue. In the experimental group, the detection rate, sensitivity, accuracy rate, and false negative rate of the carbon-nanoparticles suspension were 96.7% (29/30), 87.5% (7/8), 93.3% (28/30), and 12.5% (1/8), respectively compared with 92.8% (26/28), 66.7% (4/6), 85.7% (24/28), and 33.3% (2/6), respectively, of the control group. There is no significant difference in both groups (P>0.05). Conclusion The application of carbon-nanoparticles suspension facilitate sentinel lymph node detection and histological evaluation and therefore, could be an important adjunct to sentinel lymph node biopsy in oral tongue squamous cell carcinoma.
Objective To assess the effectiveness of interactive workshop intervention measures between children and parents inonimproving oral health literacy of parents and oral health behavior of children. Methods We compared OHL and OHB score were compared among intervention group (A), parallel control group (B) and control group (C) before and after intervention. Results Compared with baseline, parents’ OHL score (t=22.369, P<0.001) and OHB scores (t=31.100, P<0.001) of intervention group were significantly increased 3 months later. Whereas parents’ of parallel control group (OHL: t=1.892, P=0.061; OHB: t=1.965, P=0.052), blank control group (OHL: t=1.56, P=0.120; OHB: t=1.591, P=0.114) had no significant changes.there were statistically significant differences among 3 groups of parents’ OHL (F=131.590, P<0.001) and OHB score (F=203.784, P<0.001) . Pairwise comparisons.There were statistically significant differences (P<0.001) between OHL and OHB before and after the intervention. Conclusion Interactive workshops intervention between children and parents can promote parental OHL and children oral health care greatly.
Objective To investigate the clinical and pathological characteristics of the parotid gland tumor in adolescent for providing clinical evidence for its treatment. Methods The clinical and pathological data of 31 adolescents(10-19 years old) from Jan. 2003 to Dec. 2011 were retrospectively studied and compared with 516 adult cases at the same time. Results 38.7%(12/31) of the parotid gland tumors in adolescent were malignant, but only 17%(88/516) in adults. Among the 31 cases, 19 cases were benign tumor(61.3%), 12 cases were malignant tumor(38.7%). Among the benign cases, pleomorphic adenoma was the most common diseases, which accounted for 89.5%(17/19). Mucoepidermoid carcinoma(5/12) was the most common malignancy. All of the 31 cases were treated surgically, and 2 malignant cases were treated combined with postoperative radiotherapy. Conclusion The clinical and pathological features of parotid gland tumors in adolescent are different from those in adults, and more attention should be paid to this phenomenon. Operative treatment is the preferred treatment of parotid gland tumor in adolescent, which should be early and thorough. Thus far, there is great dispute on postoperative radiotherapy.
Objective To investigate the effect of Duraphat in the prevention of dental caries of abutment teeth in removable partial denture. Methods 100 patients who suffered from dentition defect were recruited. We used self-control methods.Abutment teeth of one side were randomly assigned to control group, abutment teeth of another side were assigned to experimental group. In experimental group, Duraphat was applied every six months. The prevalence of caries of abutment teeth of removable partial denture was recorded 3 years later. Results The data showed that the caries prevalence of experimental side was significantly lower than the control side (P<0.01). Conclusion It is a simple and effective way to prevent caries in the abutment teeth of removable partial denture with Duraphat.
Vitamin D is an essential fat-soluble vitamin that can be synthesized in the human skin when exposed to sunlight or obtained through dietary means. At present, Vitamin D deficient or insufficient has become a hot topic, which not only affects the health of skeletal muscle but also promotes the occurrence and development of other diseases, such as cancer, diabetes, and periodontitis. Vitamin D supplementation can increase the bone density, inhibit the absorption of alveolar bone and reduce teeth loss. The specific mechanism may be related to bone metabolism or immune regulation of vitamin D. This review focuses on the research progress of the influence of vitamin D on periodontitis.
With the increase of the public concerns about the temporomandibular disorders, the abnormal posture of head had attracted more and more attention. This article will discuss the correlation between the posture of forward head and temporomandibular disordres from several perspectives.
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