With the advent of dental operating microscope, periradicular microsurgery significantly improved success rate of traditional periradicular surgery, which includes periradiacular curettage, apicoectomy and retrograde filling. The present paper summarizes indication, apical sealing inspection, incision and flap design in anterior aesthetic region, and healing criteria for periradicular microsurgery.
Objective To construct the Beagle canine periodontal defect model and to observe the effect of periodontal tissue defect repairment of the periodontal membrane stem cells-dental follicle stem cells composite membrane. Methods Dog follicle stem cells (dDFSCs) and dog periodontal ligament stem cells (dPDLSCs) were isolated enzymatically and ex-panded in vitro. The dDFSCs, dPDLSCs and the mixed cells were used to make cell sheets separately. Then, three types of cell sheets were transplanted to dental root surfaces having three-wall periodontal defects in an allogeneic manner, and bone defects were filled with hydroxyaptite-tricalcium phosphatel (HA-TCP). The group only filled with HA-TCP was set as the control group. The periodontal clinical indices were evaluated at the time of 1 week and 2, 4, 6, 8 and 12 weeks after surgery. 12 weeks after surgery, the animals were sacrificed and decalcified specimens were prepared. Healing of the periodontal defects was evaluated histologically and histometrically. Results Periodontal clinical examination, histological and histometrical analysis indicate that the periodontal healing of cell sheets groups were superior to the control group, and the mixed cells sheets group was superior to the other two groups (P<0.05). Conclusion Allogeneic composite cell sheets of dDFSCs and dPDLSCs shows better effects in the repairment of Beagle periodontal tissue defect.
Objective To observe the clinical effect of two-direction inclined maxillary sinus floor augmentation from alveolar crest. Methods Sinus floor were augmented on the same site from two directions with the transalveolar technique. Firstly, lower sinus floor were augmented from the non-implant direction. Secondly, sinus floor were augmented with simultaneous placement of dental implants from the presupposed implant direction. Results Postoperative cone beam computerized tomography (CBCT) proved good effects of sinus floor augmentation, with satisfactory positional relationship with the adjacent teeth. The implant tips were covered by mucous, with no nasal hemorrhagic secretions and no obvious pain. No implant fell off within 6 months after surgery. Conclusion Two-direction maxillary sinus floor augmen-tation from alveolar crest is a possible choice to augment inclined maxillary sinus floor.
Objective To observe the effect of different etching time of citric acid on enamel blocks to acquire a reliable in vitro model for early enamel caries, and explore more effective experiment method for enamel demineralization.Methods Human premolars were selected and made into enamel blocks. The morphologies of enamel blocks surfaces etched by 10% citric acid for different time periods (90 s, 120 s, 150 s) and partially saturated acid buffer demineralization system for a week were observed by scanning electron microscope. And the surface micro hardness of these specimen before and after demineralization were tested by the micro hardness tester.Results After demineralization, enamel surface had an obvious acid etching appearance. In the 90 s etching time group, only a small part of enamel prism lattice was demineralized and dissolved, and the ability of demineralization was limited. In 120 s etching time group, the morphology of enamel blocks surface was similar to natural early enamel lesions, like the honeycomb. In the 150 s etching time group, the enamel surface had an acid corrosion damage morphology, and it was excessive etched. However,the demineralization effect of partially saturated acid buffer demineralization system was relatively low.Conclusion Citric acid has a strong etching effect, and its ability of demineralization is enhanced with the extension of time. The model of early enamel lesions can be obtained by 10% citric acid for 120 s.
Objective To explore influence of artesunate on T-bet /GATA-3 equilibrium of peripheral blood in oral lichen planus.Methods 18 OLP patients were selected,and peripheral blood mononuclear cells (PBMCs) were isolated by density gradient centrifugation. The cells were cultured and treated with different concentrations (0, 1, 100 μmol/L) of artesunate. Reverse transcription polymerase chain reaction (RT-PCR) and Western blot were applied to detect theT-bet and GATA-3 mRNA and protein expression respectively.Results The T-bet/GATA-3 mRNA and protein expressions in groups treated with artesunate (1 μmol/L & 100 μmol/L) were higher than that of control group (treated without artesunate) (P<0.05), and the expressions were improved significantly in high concentration group (100 μmol/L) compared with low concentration group (1 μmol/L) (P<0.05).Conclusion Artesunate can regulate the T-bet/GATA-3 balance in OLP effectively.
Objective To reduce radiotherapy complications of patients suffered from malignant tumor in head and neck.Methods Study group (247 cases of patients suffered from malignant tumoer in head and neck) were given the whole course intervention of dentist while doing radiotherapy, the incidence of the complication study group was investigated and compared with control group (213 cases).Results There was no difference between study group and control group in short-term complications. But for the long-term complications, the incidence in study group was considerably less than that of control group.Conclusion The whole course intervention of dentists can reduce the radiotherapy complications in head and neck effectively and improve the life quality.
Objective To compare the clinical effect of the zirconia inlay and gold alloy inlay in the restoration of the second class defect of molar with vital pulp.Methods 60 teeth were randomly divided into zirconia inlay group and gold alloy inlay group, with 30 teeth in each group. Evaluate the restoration effect in 2 group at 1-year follow-.Results At 1-year follow-up, according to US Public Health Service Criteria, the success rate in anatomy zirconia group was93.53%, which was statistically higher than that of the gold alloy group (P<0.05). In the comparison of aesthetics, the anatomy zirconia group was superior to that of the gold alloy group.Conclusion The aesthetic and overall success rate of the anatomy zirconia inlay is superior to that of the gold alloy inlay in the restoration of the second class defect of molar with vital pulp.
Objective To investigate the anatomical features of alveolar bone in gummy smile patients with cone beam computed tomography (CBCT), and provide the reference for miniscrews implanted in anterior alveolar crest.Methods A total of 63 cases of adults with gummy smile were selected for the study and the CBCT data of jaw bones were obtained. The mesiodistal interradicular distances, buccal-lingual thickness and buccal cortical bone thickness were measured at three different level which included 4 mm,6 mm and 8 mm above the alveolar crest.Results The mesiodistal interradicular distances increased along with distance between measure level and alveolar crest.(P<0.05). The interradicular distance were the least when measured between central incisor and lateral incisor (P<0.05). The interradicular space between central incisors presented the least buccal-lingual thickness (P<0.05). No significant differences were observed between the other thicknesses of anterior interradicular spaces (P>0.05). The buccal cortical bone thickness increased along with distance between measure level and alveolar crest (P<0.05). The thicknesses were the least between central incisors while the most between lateral incisor and canine (P<0.05).Conclusion The mesiodistal interradicular distances,buccal-lingual thickness and buccal cortical bone thickness are found increased with the height level. Given the most bone mass and cortical bone thickness, canine and lateral incisor interval can be recommended as the place for the miniscrews inserting.
Objective To observe the clinical effect of Er:YAG laser for pulpotomy in young permanent incisors.Methods 40 young permanent incisors with xeposed pulp were divided into 2 groups respectively. Teeth in laser group were treated with mineral trioxide aggregate combined with Er:YAG laser for pulpotomy with teeth in control group were treated with mineral trioxide aggregate (MTA) pulpotomy only. Patients were scheduled for follow-up after 1, 3, 6, 12 months to undergo clinical and radiographic examination.Results 18 of the treated teeth in control group and 19 of the treated teeth in laser group showed no clinical or radiographic signs of failure during the follow-up period. There was no significant difference between the two groups.Conclusion Pulpotomy with Er:YAG laser and direct capping with MTA was a successful and effective treatment for pulp exposure in young permanent incisors.
Objective To assess the impact of chronic pharyngitis on oral health related quality of life.Methods Consecutive patients with chronic pharyngitis were recruited. 130 patients and 362 healthy controls were investigated by the questionnaire according to the Chinese version of the oral health impact profile-14 (OHIP-14). Spearman correlation anaylsis and multiple linear regression were performed to analyze the association between OHIP-14 and variables.Results The total OHIP-14 scores of patients with chronic pharyngitis (9.52±7.41) was higher than controls (7.45±7.90), including functional limitations, physical pain subscale, psychological discomfort. Spearman correlation analysis showed that OHIP-14 scores were correlated with age, visual analogue scale (VAS) and the index of decayed-missed-filled teeth (DMFT) (rs=0.238, P=0.01; rs=0.473, P<0.001; rs=0.26, P=0.005). In addition, there was highly significant association between the OHIP-14 score and VAS, as well as DMFT (steβ=0.353, P<0.001; steβ=0.186, P=0.037; R 2 =0.294) . Conclusion Chronic pharyngitis has impacts on the oral health related quality of life. Enhanced prevention is suggested on the patient who has higher OHIP-14 score.
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