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Shaohong HUANG,Weijia LIU

2019 Vol.27(1): 2–7    [Abstract] ( )    [RICH HTML ] ( )   [PDF 969 KB ]( )

CHEN Faming,GAO Lina,CHEN Fang

2019 Vol.27(1): 9–16    [Abstract] ( )    [RICH HTML ] ( )   [PDF 984 KB ]( )

XIE Wenqiang,WANG Jieqi,ZHUANG Peilin,LI Xiaoyu,ZHENG Meihua,ZHANG Wen,WEI Peiling

2019 Vol.27(1): 17–22    [Abstract] ( )    [RICH HTML ] ( )   [PDF 4467 KB ]( )

YIN Xiaoping,XIONG Huacui,CHEN Ke,HUANG Ying,XU Shuaimei

2019 Vol.27(1): 23–29    [Abstract] ( )    [RICH HTML ] ( )   [PDF 2610 KB ]( )

HONG Yurui,ZHOU Hailan,GAO Yongbo

2019 Vol.27(1): 30–34    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1702 KB ]( )

CHANG Lin,LI Dehong,ZHU Pengfei,YI Chunyan,ZHANG Yanan,YANG Xianghong

2019 Vol.27(1): 35–40    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1763 KB ]( )

WANG Shipeng,ZHANG Andong,CHENG Li,CHEN Baoyong,WEN Li,LIU Huawei

2019 Vol.27(1): 41–45    [Abstract] ( )    [RICH HTML ] ( )   [PDF 2191 KB ]( )

Nian YU,Yong LU

2019 Vol.27(1): 46–49    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1807 KB ]( )

DENG Jiaxin,CHEN Yue,CHEN Yuan,WANG Yan

2019 Vol.27(1): 50–55    [Abstract] ( )    [RICH HTML ] ( )   [PDF 806 KB ]( )

ZHONG Lidong,KONG Weidong

2019 Vol.27(1): 56–60    [Abstract] ( )    [RICH HTML ] ( )   [PDF 731 KB ]( )

LI Junliang,YANG Weidong

2019 Vol.27(1): 61–65    [Abstract] ( )    [RICH HTML ] ( )   [PDF 903 KB ]( )

Shaohong HUANG,Weijia LIU

2019 Vol.27(1): 2–7    [Abstract] ( )    [RICH HTML ] ( )   [PDF 969 KB ]( )

As a professional method to prevent decayed teeth and an oral public health project, pit and fissure sealant is widely used domestically. How to evaluate the effect and benefit of the community pit and fissure closure project, especially the community full coverage pit and fissure closure project, requires investigation. The Guangzhou Children′s Pit and Fissure Sealing Project was carried out in an orderly manner and was administered normatively. A retrospective cohort study with use of a sample survey was used in this program. According to cavity occurrence and reservations of sealant in the first permanent molar, the samples were divided into the following two groups: the sealing group with indication and the sealing group without indication. Reservations of sealant, cavity incidence, reduced incidence, net profit, cost-effectiveness and cost-benefits of the program were evaluated. Some promotable experiences were summarized during this project. Various relevant theories and reports of the pit and fissure sealant project evaluation were reviewed and previous studies were discussed in this article. By analyzing the methods and results of the pit and fissure sealant project in Guangzhou, suggestions are made for project evaluation, especially sample grouping and evaluation indicators, which was refer to a further study for the pit and fissure sealing project.

CHEN Faming,GAO Lina,CHEN Fang

2019 Vol.27(1): 9–16    [Abstract] ( )    [RICH HTML ] ( )   [PDF 984 KB ]( )

Periodontitis is the most common oral disease and has a high incidence in humans. Periodontitis seriously affects the function of the oral and maxillofacial systems and is the most important cause of tooth loss in adults. In addition, as a long-term and persistent source of infection, periodontitis can not only trigger chronic inflammation and immune responses but also has an important impact on systemic health. Traditional periodontitis treatment focuses on inflammation control, and although this can prevent or delay the progression of the disease, satisfactory periodontal lesion tissue regeneration is difficult to obtain. With the introduction of new technologies and new materials such as guided tissue regeneration, bone grafting, growth factors and biological materials for the treatment of periodontitis, the method of periodontal tissue regeneration is more abundant, and the clinical effect has been greatly improved. In the future, stem cell transplantation and endogenous regeneration strategies are expected to become important methods for physiological and functional regeneration of periodontal lesions. This article briefly reviews the basic research and clinical application of periodontal tissue regeneration and forecasts the future development prospects and opportunities in this field.

XIE Wenqiang,WANG Jieqi,ZHUANG Peilin,LI Xiaoyu,ZHENG Meihua,ZHANG Wen,WEI Peiling

2019 Vol.27(1): 17–22    [Abstract] ( )    [RICH HTML ] ( )   [PDF 4467 KB ]( )

Objective To investigate the physical properties of Ti-6Al-4V clasps generated by selective laser melting (SLM) with different construction directions and to compare these clasps with cast clasps, which could provide a basis for fabricating SLM clasps with high precision and excellent mechanical properties. Methods Ti-6Al-4V clasps were fabricated by SLM at 0 degrees (SLM0 group), 45 degrees (SLM45 group) and 90 degrees (SLM90 group) (n = 12). Twelve clasps were cast by the casting method as the control group. Meanwhile, four metal abutments were cast randomly as the abutments of the four groups. X-ray was used to detect cracks in the clasps of each group. The roughness of the clasps was measured by confocal microscopy, the fitness tests between clasps and abutment were processed by stereomicroscopy, and the microstructure of clasps in each group was observed under a metallographic microscope to evaluate the physical properties. Results There were 0-8 visible cracks in the casting group but no obvious defects in the SLM groups. The maximum surface roughness was observed in the cast group (18.102 ± 3.762) μm, while the minimum roughness was observed in the SLM90 group (5.942 ± 1.486) μm (P < 0.05). There was no statistically significant difference in surface roughness between the SLM0 group [(8.711 ± 2.378) μm] and the SLM45 group [(8.513 ± 1.161) μm]. Fitness was worst in the casting group [(68.445 ± 14.876) μm] and best in the SLM90 group [(33.417 ± 5.880) μm] (P < 0.05). There was no statistically significant difference in fitness between the SLM0 group [(52.917 ± 12.102) μm] and the SLM45 group [(50.889 ± 7.011) μm]. In addition, the growth direction of the β grains was roughly parallel to the build direction, and acicular α grains were present between β grains. SLM was composed of fine grains, while the cast group had large grains. Conclusions Specimens generated by SLM had finer grains than cast specimens. In addition, SLM90 clasps had the highest fitness and the lowest surface roughness.

YIN Xiaoping,XIONG Huacui,CHEN Ke,HUANG Ying,XU Shuaimei

2019 Vol.27(1): 23–29    [Abstract] ( )    [RICH HTML ] ( )   [PDF 2610 KB ]( )

Objective To investigate the effects of leptin on the proliferation of stem cells from human stem cells from the apical papilla (hSCAPs) and the expression of osteogenic/dentinogenic genes in vitro to provide an experimental basis for the sustainable development of young permanent teeth. Methods The tissue block method was used to isolate and culture hSCAPs from the apical papilla of the immature third permanent molar. The expression of leptin and OBRb in hSCAPs was detected using immunocytofluorescence staining, western blotting and reverse transcription polymerase chain reaction (RT-PCR) analysis. The hSCAPs was treated with 0.1 μg/mL of leptin (0.1 μg/mL group) or 1.5 μg/mL of leptin (1.5 μg/mL group) at different time points. The control group was treated with alpha-MEM medium. Cell proliferation was measured using the CCK8 assay and cell cycle analysis. QRT-PCR was used to detect the expression of related osteoblast/odontogenic genes for alkaline phosphatase (ALP), dentin matrix protein -1 (DMP-1), dentin sialophosphoprotein (DSPP), and osteocalcin (OCN) mRNA. The differences between the treatment groups and the control group were analyzed statistically using one-way ANOVA followed by Bonferroni analysis. Results The expression of both leptin and OBRb were found in hSCAPs. Compared with the control group, the cell proliferation capacity and S phase cells in the treatment groups were higher than those in the control group, with the 1.5 μg /mL group displaying higher levels than 0.1 μg /mL group, and the treated hSCAPs demonstrated a higher proliferation rate and a higher expression of ALP, DSPP, and DMP-1 from day 3 to day 7, with the 1.5 μg /mL group displaying higher levels than 0.1 μg /mL group , and the difference was statistically significant (P < 0.05), at day 7. The treated hSCAPs demonstrated a lower expression of ALP, DSPP, and DMP-1. Compared with the control group, the treated hSCAPs demonstrated a higher expression of OCN from day 7 to day 14, with significantly higher expression in the 1.5 μg /mL group compared to the 0.1 μg /mL group. Conclusion Leptin may promote cell proliferation and upregulate the expression of relative osteogenic/dentinogenic genes.

HONG Yurui,ZHOU Hailan,GAO Yongbo

2019 Vol.27(1): 30–34    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1702 KB ]( )

Objective To investigate the clinical effect of restoration of posterior teeth with machinable CAD/CAM resin hybrid ceramic (VITA Enamic) onlays after root canal treatment. Methods 136 posterior teeth restored after root canal treatment in our hospital were selected as the research subjects. The posterior teeth were restored chairside with CAD / CAM ceramic onlays to recover occlusion relation and protect residual dental tissues. With 68 teeth in each group, one group was restored with a machinable CAD / CAM resin hybrid ceramic (VITA Enamic) while the control group received zirconia-reinforced lithium silicate ceramic (VITA Suprinity). Before bonding, all the onlays were examined for good adjacency, fitness and occlusion, and then the adhesive surface was etched with hydrofluoric acids. After isolating the rubber dams in the mouths, the onlays were bonded with dual-cure resin cements. The patients were followed up for 24 months to compare the degree of prosthesis integrity, marginal fitness, gingival health, dental integrity, color matching and secondary caries. Results After restoration, all the onlays were in harmony with the surrounding teeth with good aesthetic effect and suitable marginal fit. Two years later, there were no significant differences in the marginal fitness, gingival health, dental integrity or secondary cavities between the two groups (P > 0.05). In terms of restoration integrity, the VITA Enamic onlays (100%) were intact and displayed good retention. The group that received VITA Suprinity had 6 onlay (9.23%) fractures and a success rate of 90.77%; however, the residual dental tissues did not break. The difference of prosthesis integrity between the two groups was statistically significant (χ 2= 4.45, P < 0.05). Conclusion Chairside CAD/CAM resin hybrid ceramic (VITA Enamic) onlays can quickly restore posterior teeth after root canal therapy and better protect the residual dental tissue.

CHANG Lin,LI Dehong,ZHU Pengfei,YI Chunyan,ZHANG Yanan,YANG Xianghong

2019 Vol.27(1): 35–40    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1763 KB ]( )

Objective To investigate the changes of the upper airway shape and respiratory function in patients with mild and moderate obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after wearing mandibular advancement snore stopping devices (MASSD), providing a reference and basis for the treatment mechanisms and clinical efficacy of MASSD for patients with mild and moderate OSAHS. Methods Sixty patients who were diagnosed with mild and moderate OSAHS by polysomnography were selected. Snoring frequency, the apnea hypopnea index and lowest oxygen saturation in 60 patients before and after treatment were compared. The patients’ upper airways were scanned by CBCT before and after wearing MASSD. In Vivo Dental software was used to reconstruct the three-dimensional shape of upper airway. The upper airway sagittal diameter, the coronal diameter, the minimum cross-sectional area and the volume of each segment were measured. The snoring frequency, the apnea hypopnea index and the lowest oxygen saturation were compared before and after treatment. Results Before wearing MASSD, the snoring frequency, the apnea hypopnea index, and the minimum oxygen saturation of 60 patients were [946 (542,1 010)], (20.61 ± 5.19), and (78 ± 8)%, respectively. After wearing MASSD, the snore frequency [19(11,30)] and the respiratory disorder index (10.86 ± 4.31) decreased significantly and the minimum oxygen saturation increased (92 ± 3)%. Compared with before wearing MASSD, no statistically significance differences were detected (P > 0.05) except for the sagittal diameter and coronal diameter of the surface of the palatum durum. The sagittal diameter and the coronal diameter of each plane of the airway increased, and the minimum cross-sectional area of each section of the airway and the volume of each section of the airway displayed varying degrees of significant increases (P < 0.001) after wearing MASSD. Conclusion Wearing MASSD can open the airways of patients with mild and moderate OSAHS and increase the airway volume of the upper airway to improve the respiratory function.

WANG Shipeng,ZHANG Andong,CHENG Li,CHEN Baoyong,WEN Li,LIU Huawei

2019 Vol.27(1): 41–45    [Abstract] ( )    [RICH HTML ] ( )   [PDF 2191 KB ]( )

Objective To summarize the incidence, clinical manifestations, diagnosis and treatment of basal cell nevus syndrome and to provide reference for clinical diagnosis and treatment. Methods Retrospective analysis of 4 cases of basal cell nevus syndrome admitted to the General Hospital of PLA during January 2017 to January 2018 and recent cases reported in the literature. Results In this study, 1 males and 3 females were included. The patients included a mother and her child. All 4 cases were surgically resected. Pathological reports included all keratocysts of the jaws. There has been no recurrence since follow-up. Through literature summarization and analysis, the clinical manifestations of this syndrome were found to be diverse. Typical clinical manifestations include multiple keratocysts of the jaws, multiple blepharospasms or cancers, deformities of the spine or ribs, increased brachial distance, eye diseases or special face intracranial calcification. Conclusion Basal cell nevus syndrome is an autosomal dominant genetic disorder. The clinical manifestations are diverse and the diagnosis is often overlooked. The incidence of cysts in the jaws is one of the important clinical manifestations of this syndrome. Early diagnosis and proper treatment improve patient survival and quality of life.

Nian YU,Yong LU

2019 Vol.27(1): 46–49    [Abstract] ( )    [RICH HTML ] ( )   [PDF 1807 KB ]( )

Objective To investigate the treatment methods of chronic prolonged mandibular dislocation. Methods Surgical reduction was performed in a case of temporomandibular joint dislocation over 6 months after manual reduction failure. The flap was removed under general anesthesia, and the bone of the condyle were removed. The articular disc was aligned and incision was sutured, and the procedure was combined with intermaxillary fixation for a correct occlusion and traction. After the operation, the surgical efficacy was observed, and the related literature was reviewed. Results The patient recovered well after the operation; the mouth opening was 3 cm, and the occlusion was normal. No recurrence was observed after 10 months of follow-up. The literature shows that surgery is a common treatment for temporomandibular joint dislocation after the failure of manual reduction, and postoperative patient education can reduce recurrence and complications. Conclusion Surgery combined with intermaxillary traction can effectively treat chronic prolonged mandibular dislocation.

DENG Jiaxin,CHEN Yue,CHEN Yuan,WANG Yan

2019 Vol.27(1): 50–55    [Abstract] ( )    [RICH HTML ] ( )   [PDF 806 KB ]( )

Hemangioma is the most common vascular benign tumor in infants and young children, 60% of which occur in the oral maxillo-facial region. One characteristic of oral and maxillofacial hemangioma is spontaneous regression, which generally does not require treatment; however, a few hemangiomas can produce complications including ulceration, functional disorders and dis?gurement, which require active treatments. Currently, the treatment of oral and maxillofacial hemangioma include drug treatment, laser treatment and surgical treatment. The drugs used to treat hemangioma mainly include beta blockers, glucocorticoids, alpha-interferon, imiquimod and antitumor drugs. Drug therapy is suitable for multiple, rapidly proliferating hemangiomas and hemangiomas that affect vital organ function or endanger life. Laser therapy can be applied to the early treatment of rapidly growing hemangiomas at exposed sites. Surgical treatment is suitable for proliferative hemangioma with serious complications, the reconstruction of any external deformity and the repair of a scar after an ulcer. Combined therapy and the development of new technologies provide new directions for the treatment of hemangioma but the efficacy remains to be proven by large sample prospective studies. Clinicians should appropriately evaluate the patients with hemangioma and develop individualized treatment programs for patients with treatment indications. This article reviews the efficacy, mechanism, clinical application and adverse reactions of different treatment methods and provides references for clinical treatment.

ZHONG Lidong,KONG Weidong

2019 Vol.27(1): 56–60    [Abstract] ( )    [RICH HTML ] ( )   [PDF 731 KB ]( )

Invisible appliance technology is a novel orthodontic technology that uses computer aided design and polymer materials to achieve a more aesthetic and comfortable treatment. Compared with traditional lip-bracket orthodontic treatments, the greatest advantages of an invisible appliance are aesthetics. In the orthodontic process, the control of the anterior teeth may not be accurate, which often directly affects the patient′s postoperative side appearance; however, in clinical practice, there is still a large deficiency in the control of the anterior tooth torque by an invisible appliance compared to traditional lip-bracket orthodontic treatments. The factors related to the expression efficiency of anterior tooth torque include the combination of morphology and position of different types of brackets and wires, the tooth movement mode and clincheck design. This article reviews the factors that influence lingual orthodontics and clear aligner therapy in the treatment of anterior tooth torque.

LI Junliang,YANG Weidong

2019 Vol.27(1): 61–65    [Abstract] ( )    [RICH HTML ] ( )   [PDF 903 KB ]( )

Important guarantees of the success of root canal therapy include being familiar with the anatomical features of root canal system, good root canal preparation and complete root canal filling. With the development of medical imaging technology, three-dimensional reconstruction technology has been widely applied in root canal morphology, root canal preparation, root canal filling quality, root canal retreatment efficiency, three-dimensional finite elements and other related research. The reconstructed 3D images can be observed qualitatively and quantitatively from different angles and levels, which aid in the understanding of root canal anatomy and evaluation of the operation effect on all aspects of root canal therapy, providing important guiding significance for clinical operation. The application of 3D reconstruction technology based on micro-CT in the research of root canal anatomy, root canal preparation, root canal filling, root canal retreatment efficiency and three-dimensional finite element analysis are reviewed. The results of a literature review showed that the resolution of micro-CT is high. Furthermore, three-dimensional reconstruction can accurately display the fine anatomical morphology of a root canal, accurately measure the volume and morphological changes of root canal before and after root canal preparation, accurately measure the incidence and volume of the void after root canal filling and accurately calculate the volume changes of the root canal filling materials before and after root canal retreatment. Micro-CT is the gold standard for the morphological study of the root canal system and quality analysis of root canal preparation and filling. After three-dimensional reconstruction with micro-CT scans, a three-dimensional finite element model can be established to simulate the process of root canal therapy and stress analysis. This method can be used to analyze the stress distribution of root canal preparation instruments and the influence of root canal preparation on the stress distribution of tooth tissue and the root canal wall in the process of root canal filling. Then, suitable operation methods can be selected to prevent instrument breakage and root fracture. The application of three-dimensional reconstruction-based micro-CT is of great value in the evaluation of root canal morphology and treatment.

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