Journal of Prevention and Treatment for Stomatological Diseases ›› 2017, Vol. 25 ›› Issue (2): 93-96.DOI: 10.12016/j.issn.2096-1456.2017.02.005

• Basic Study • Previous Articles     Next Articles

Antibacterial effects and tensile bonding strength of orthodontic adhesive containing nanohydroxyapatite

Zhen-xia LI1,2(), Ting-ting CHEN3, Pei-lin LI1,2, Jing XUE1,2, Qiang ZHANG3()   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
    2. West China School of Stomatology, Sichuan University, Chengdu 610041, China
    3. Shenzhen Maternity & Child Healthcare Hospital, Shenzhen 518048, China
  • Received:2016-06-28 Revised:2016-09-30 Online:2017-02-20 Published:2018-09-03


李振霞1,2(), 陈婷婷3, 李沛霖1,2, 薛晶1,2, 张强3()   

  1. 1. 口腔疾病研究国家重点实验室,四川大学,四川 成都(610041)
    2. 四川大学华西口腔医学院,四川 成都(610041)
    3. 南方医科大学附属深圳市妇幼保健院口腔病防治中心,广东 深圳(518048
  • 作者简介:

    【作者简介】 李振霞,在读研究生,

  • 基金资助:


Objective To evaluate the tensile bonding strength (TBS) and antibacterial properties when an orthodontic adhesive was added with nanohydroxyapatite (nHAp). Methods Light cure orthodontic adhesive (Grengloo) was blended with 2% TiO2 containing nHAp nanoparticles by 0%、10%、20%、30% (w/w), while the control was not blended with nHAp. Brackets were bonded to extracted premolars by these new adhesives. TBS of 5groups were determined, and the adhesive remnant index (ARI) scores were assessed. Composite discs specimen were prepared, incubated with bacterial suspension for 48 h, and tested for antibacterial properties. Results No significant difference was found in ARI. The colony unit counts and lactate productionof the groups containing 2%TiO2 were significantly reduced. The colony unit counts and lactate production were without relationship with nHAp. The tensile bonding strength drastically decreased when containing more than 10% nHAp. Conclusin nHAp might not enhance the antibacterial effects of Grengloo.

Key words: Nanohydroxyapatite, TiO2, Orthodontic adhesive, Antibacterial, Tensile bonding strength93/img_1.jpg163.01.0


目的 研究纳米羟基磷灰石及二氧化钛对托槽粘接剂的抗菌性能及粘接强度的影响。方法 在纳米二氧化钛改性的托槽粘接剂(Grengloo)中加入质量分数0%、10%、20%、30%的纳米羟基磷灰石,于离体前磨牙上粘接托槽,测量拉伸粘接强度与粘接剂残留量。粘接树脂制成的圆片试样与菌悬液共培养48 h,测定细菌活性与代谢。结果 2%二氧化钛不影响粘接剂的粘接强度且可提高粘接剂的抗菌性。10%纳米羟基磷灰石使粘接剂的粘接强度明显降低。四组粘接剂残留指数差异无统计学意义。纳米羟基磷灰石无明显抗菌性。结论 纳米羟基磷灰石不能明显提高Grengloo托槽粘接剂的抗菌性,随着其含量的增加粘接强度明显降低。

关键词: 纳米羟基磷灰石, 二氧化钛, 托槽粘接剂, 抗菌性, 拉伸粘接强度

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