Journal of Prevention and Treatment for Stomatological Diseases ›› 2017, Vol. 25 ›› Issue (10): 638-640.doi: 10.12016/j.issn.2096-1456.2017.10.005

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The analysis of expression of HAase in oral squamous cell carcinoma

Jingxu WANG1(), Guiqing LIAO2   

  1. 1. Department of Stomatology Guanzhou Medical University Guangzhou 510182 China.
    2. Department of Oral and Maxillofaial Surgery Guanghua Shool of Stomatology Sun Yet-sen University Guangzhou 510182 China
  • Received:2017-05-31 Revised:2017-08-04 Online:2017-10-27 Published:2018-09-03

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Abstract:

Objective To evaluate the expression of HAase in Oral Squamous Cell Caricinoma (OSCC). Methods The distribution and expression of HAase in 21 patients with OSCC and their resecetions with tumor-free margins were examined by immunohistochemistry method.Results HAase were mainly immunostained in tumor tissue. The expression of HAase in oral cancer with nodal metastasis and low pathological grades were higher than that with no nodal metastasis and high pathological grades (P < 0.05), whereas no difference between the TNM stages (P > 0. 05). Conclusion The HAase levels were high in oral squamous cell carcinoma tissues, and rising in patients with lymph node metastasis and poorly differentiated.

Key words: Oral, Squamous cell carcinoma, Hyaluronidase, Tumor, Immunohistochemistry

CLC Number: 

  • R739.8

Figure 1

The expression of HAase in OSCC"

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