Journal of Prevention and Treatment for Stomatological Diseases ›› 2017, Vol. 25 ›› Issue (10): 652-655.DOI: 10.12016/j.issn.2096-1456.2017.10.008

• Cinical Study • Previous Articles     Next Articles

The short-term efficacy of implant in the treatment of patients with dentition defect caused by chronic periodontitis

Hua ZHANG()   

  1. Department of Dental Implant Haizhu District Oral Hospital Guangzhou 510220 China
  • Received:2016-10-26 Revised:2016-12-12 Online:2017-10-27 Published:2018-09-03

种植修复治疗慢性牙周炎牙列缺损的短期疗效

张华()   

  1. 广州市海珠区口腔医院种植科,广东广州(510220
  • 作者简介:

    【作者简介】 张华,主治医师,硕士, Email: guoyuqing2015@163.com

Abstract:

Objective To investigate the short-term efficacy of implant in the treatment of patients with dentition defect caused by chronic periodontitis. Methods 53 patients with mild to moderate chronic periodontitis treated in our hospital from June 2014 to May 2015 were selected as observation group, and 53 patients without periodontal diseases in the same period were selected as control group. The plaque index (PLI), sulcus bleeding index (SBI), periodontal probing depth (PD) and gingival papilla index (PIS) were measured at six months and one year after operation, respectively. Interleukin-6 (IL-6), interleukin-8 (IL-8), high sensitive C-reactive protein (hs-CRP) and tumor necrosis factor-α (TNF-α) were detected at six months and one year after operation, respectively. At the last follow-up, the survival rate of two groups were calculated. Results One year after operation, 5 of the 64 implants in the observation group failed compared with 2 of the 71 implants in the control group. There was no statistical difference in the implant survival rate between the two groups (92.19% vs 97.18%, P=0.191). There was no significant difference in SBI (t=0.936, P=0.351)、 PLI (t=0.457, P=0.649)、PIS (t=1.132, P=0.217)、PD (t=0.957, P=0.341) between the two groups at six months after operation. One year after operation, the periodontal index of the observation group was higher than that of the control group SBI (t=5.297, P=0.000)、 PLI (t=2.341, P=0.021)、 PIS (t=8.218, P=0.000) and PD (t=6.492, P=0.000). The levels of IL-6 (t=6.463, P=0.000)、 IL-8 (t=7.202, P=0.000)、 hs-CRP (t=4.237, P=0.000) and TNF-α (t=6.194, P=0.000) in the observation group were higher than those in the control group at six months after operation. One year after operation, the level of inflammatory factors in the observation group was higher than that in the control group IL-6 (t=12.835, P=0.000)、 IL-8 (t=13.207, P=0.000)、 hs-CRP (t=11.319, P=0.000) and TNF (t=8.117, P=0.000). Conclusion Implant as the treatment of patients with dentition defect caused by chronic periodontitis obtained satisfied short-term effect, but its long-term efficacy remains to be further verified.

Key words: Implant restoration, Chronic periodontitis, Dentition defect, Inflammatory factor, Gingival sulcus fluid, Short-term effect

摘要:

目的 探讨种植修复治疗慢性牙周炎所致牙列缺损患者的短期疗效。方法 选取2014年6月 ~ 2015年5月在广州市海珠区口腔医院行种植修复的轻中度慢性牙周炎患者53例作观察组,选取同期行种植修复的牙周健康者53例作对照组。分别于术后半年和1年时,检测两组患者种植牙菌斑指数(plaque index, PLI)、龈沟出血指数(sulcus bleeding index, SBI)、牙周袋探诊深度(periodontal probing depth,PD)和牙龈乳头指数(gingival papilla index, PIS),同时检测龈沟液白细胞介素-6(interleukin-6,IL-6)、白细胞介素-8(interleukin-8,IL-8)、高敏-C反应蛋白(high sensitive C-reactive protein,hs-CRP)和肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)。末次随访时,观察两组患者种植体有无松动、脱落情况,计算存留率。结果 术后1年随访时,观察组64枚种植体中5枚脱落,对照组71枚种植体中2枚脱落,两组术后1年种植体存留率比较无统计学差异(x2=1.179,P=0.191)。术后半年两组SBI(t=0.936,P=0.351)、PLI(t=0.457,P=0.649)、PIS(t=1.132,P=0.217)和PD(t=0.957,P=0.341)比较无统计学差异。术后1年观察组各牙周指标大于对照组,差异有统计学意义,SBI(t=5.297,P=0.000)、PLI(t=2.341,P=0.021)、PIS(t=8.218,P=0.000)和PD(t=6.492,P=0.000)。术后半年观察组IL-6(t=6.463,P=0.000)、IL-8(t=7.202,P=0.000)、hs-CRP(t=4.237,P=0.000)和TNF-α(t=6.194,P=0.000)水平明显高于对照组。术后1年观察组各炎性因子IL-6(t=12.835,P=0.000)、IL-8(t=13.207,P=0.000)、hs-CRP(t=11.319,P=0.000)和TNF(t=8.117,P=0.000)水平也高于对照组,差异具有统计学意义。结论 种植修复治疗慢性牙周炎所致牙列缺损能够获得较满意的短期疗效,但是其远期疗效尚待进一步验证。

关键词: 种植修复, 慢性牙周炎, 牙列缺损, 龈沟液, 炎性因子, 短期疗效

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