Journal of Prevention and Treatment for Stomatological Diseases ›› 2017, Vol. 25 ›› Issue (12): 803-805.doi: 10.12016/j.issn.2096-1456.2017.12.011

• Prevention and Treatment Practice • Previous Articles     Next Articles

Primary neuroendocrine small cell carcinoma of the parotid gland: A case report and literature review

Zongsheng CHENG1(), Yinhuan JIN2   

  1. 1. Department of Stomatology Chong qing city Wan zhou Distrist People’s Hospital Chong qing 404100 China;
    2. Department of Otorhinolaryngology Chong qing city Wan zhou Distrist People’s Hospital Chong qing 404100 China;
  • Received:2016-12-22 Revised:2017-04-17 Online:2017-01-04 Published:2018-09-03

Abstract:

Primary neuroendocrine small cell carcinoma of the parotid gland is a rare malignant tumor, the clinical diagnosis is difficult. This article report a primary parotid neuroendocrine small cell carcinoma which was initially diagnosed of adenoid cystic carcinoma of the parotid gland and was operated, but recurred 2 years later. The artide discuss about the characteristic of this disease and review the relevant literatures.

Key words: Small cell carcinoma, Neuroendocrine, Immunohistochemistry, Parotid gland, Tumour

CLC Number: 

  • R739.8

Figure 1

CT examination of parotid gland"

Figure 2

Immunohistochemically staining showed positive expression of CD 56 and syn in left parotid gland tumor"

Figure 3

Hematoxylin and eosin- stained of Left parotid gland tumor (× 200)"

[1] Kim JH, Lee SH, Park J, et al.Extrapulmonary small-cell carcinoma: a single-institution experience[J]. Jpn J Clin Oncol, 2004, 34(5): 250-254.
[2] Nagao T, Gaffey TA, Olsen KD, et al.Small cell carcinoma of the major salivary glands: clinicopathologic study with emphasis on cytokeratin 20 immunoreactivity and clinical outcome[J]. Am J Surg Pathol, 2004, 28(6): 762-770.
[3] Servato JP, Da Silva SJ, De Faria PR, et al.Small cell carcinoma of the salivary gland: a systematic literature review and two case reports[J]. Int J Oral Maxillofac Surg, 2013, 42(1): 89-98.
[4] Barnes L, Eveson JW, Reichart P, et al.Pathology and genetics head and neck tumours[M]. lyon: iarc press, 2005: 135-139.
[5] Xu B, Chetty R, Perez-Ordoñez B.Neuroendocrine neoplasms of the head and neck: some suggestions for the new WHO classification of head and neck tumors[J]. Head Neck Pathol, 2014, 8(1): 24-32.
[6] Kaira K, Shimizu Y, Tsuchiya T, et al.Small cell carcinoma of the parotid gland[J]. Otolaryngol Head Neck Surg, 2007, 136(2): 330-331.
[7] Ellis GL, Auclair PL, Gnepp DR.Surgical pathology of the salivary glands[M]. Philadelphia: WB Saunders Company, 1991: 108-488.
[8] Said-Al-Naief N, Sciandra K, Gnepp DR. Moderately differentiated neuroendocrine carcinoma (atypical carcinoid) of the parotid gland: report of three cases with contemporary review of salivary neuroendocrine carcinomas[J]. Head Neck Pathol, 2013, 7(3): 295-303.
[9] Alos L, Hakim S, Larque AB, et al.p16 overexpression in high-grade neuroendocrine carcinomas of the head and neck: potential diagnostic pitfall with HPV-related carcinomas[J]. Virchows Arch, 2016, 469(3): 277-284.
[10] Liu M, Zhong M, Sun C.Primary neuroendocrine small cell carcinoma of the parotid gland: A case report and review of the literature[J]. Oncol Lett, 2014, 8(3): 1275-1278.
[11] Martínez-Sáez O, Molina-Cerrillo J,Moreno García Del Real C, et al. Primary neuroendocrine tumor of the parotid gland: a case report and a comprehensive review of a rare entity[J]. Case Rep Otolaryngol, 2016, (3): 1-5.
[12] Altinay S, Firat P, Yalçin Ş, et al.Primary small cell carcinoma of the parotid: Fine needle aspiration and immunohistochemical features of a neuroendocrine variant[J]. J Cytol, 2016, 33(1): 34-36.
[13] 周福亭, 李宁毅, 卜令学, 等. 颌面部小细胞癌的临床与病理-附3例报告[J]. 中华老年口腔医学杂志, 2007, 5(1): 43-45.
[14] Kanazawa T, Fukushima N, Tanaka H, et al.Parotid small cell carcinoma presenting with long-term survival after surgery alone: a case report[J]. J Med Case Rep, 2012, 6(1):1-4.
[15] Jorcano S, Casado A, Berenguer J, et al.Primary neuroendocrine small cell undifferentiated carcinoma of the parotid gland[J]. Clin Transl Oncol, 2008, 10(5): 303-306.
[1] YIN Lifen,LIU Zhiwen,WU Hao,LING Tianyou. The expression of filaggrin in oral submucosal fibrosis [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2019, 27(9): 557-560.
[2] Wenfeng GAO,Zhiping WANG,Jing XU,Zhifeng SONG,Shuguang ZENG. Significance of the levels of Twist and Vimentin proteins in oral squamous cell carcinoma [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2018, 26(10): 639-643.
[3] Shisheng CHEN, Xiaowu YAO, Zizheng LU, Minxiao LIN. Extracapsular dissection of the upper part of parotid gland benign tumor using a tragus edge combined retroauticular hairline incision approach [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2017, 25(6): 398-400.
[4] Jingxu WANG, Guiqing LIAO. The analysis of expression of HAase in oral squamous cell carcinoma [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2017, 25(10): 638-640.
[5] Hang-hang LIU,Wu-lin HE,Ye-hong WEI,Jian-wei CHEN,Jun WEN,Shuo YANG,Ge YANG. The influence of the TNF-α induced mouse osteoblast on the proliferation of osteoclast precursor cells [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2016, 24(3): 146-149.
[6] Xiao-ping WU,Da-ming ZHANG,Wei-liang CHEN. Clinical and pathological analysis of parotid gland tumor in adolescent: report of 31 cases [J]. Journal of Prevention and Treatment for Stomatological Diseases, 2016, 24(2): 108-110.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!
This work is licensed under a Creative Commons Attribution 3.0 License.