Journal of Prevention and Treatment for Stomatological Diseases ›› 2021, Vol. 29 ›› Issue (9): 638-643.DOI: 10.12016/j.issn.2096-1456.2021.09.011

• Review Articles • Previous Articles     Next Articles

Research progress on the antibacterial properties of dental resin materials

ZHOU Zeying(),ZHANG Jingyue,NIU Ju,LIU Dandan,ZHAO Wendi,LIU Xiaoqiu()   

  1. Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China
  • Received:2020-11-24 Online:2021-09-20 Published:2021-06-18
  • Contact: Xiaoqiu LIU
  • Supported by:
    Project of Science and Technology Department of Jilin Province(20160519017JH)

牙科树脂材料抗菌性能的研究进展

周泽瑛(),张静月,牛菊,刘丹丹,赵文迪,刘晓秋()   

  1. 吉林大学口腔医院修复科,吉林 长春(130021)
  • 通讯作者: 刘晓秋
  • 作者简介:周泽瑛,住院医师,硕士,Email: 1280064956@qq.com
  • 基金资助:
    吉林省科技发展计划(20160519017JH)

Abstract:

Dental resin materials have been widely used in the treatment of dental defects. However, the polymerization shrinkage of the resin materials tends to cause microleakage and accumulation of bacterial plaque, which leads to secondary dental caries. Endowing dental resin with antibacterial properties is an important way to solve this problem. Adding antibacterial agents to dental resin is the main method to give it antibacterial properties. Antimicrobial agents are mainly divided into three types: release type, non-release type and mixed type. In terms of antibacterial effects, the selection and addition of antibacterial agents will affect the antibacterial and mechanical properties of dental resin materials; and the long-term antibacterial effect of antimicrobial agents in the oral cavity remains to be verified; as antimicrobial agents or other environmental factors can lead to drug resistance and even dormant persistent bacteria. In recent years, researchers have been committed to improving the antibacterial effect by modifying antibacterial agents. The sustained release of antimicrobial agents via carriers is also the main research direction. This paper reviews the research progress on the antibacterial properties of dental resin materials.

Key words: dental tissue defect, filling materials, dental resins, polymerization shrinkage, microleakage, secondary caries, antibacterial agent, carrier, sustained release, modification

摘要:

牙科树脂材料广泛应用于牙体缺损治疗,但树脂材料的聚合收缩易造成微渗漏,并积聚细菌菌斑,导致牙体组织出现继发龋。赋予牙科树脂材料抗菌性能是解决这一问题的重要途径之一,在牙科树脂材料中添加抗菌剂是赋予其抗菌性能的主要方法。抗菌剂主要分为释放型、非释放型及混合型三大类。抗菌效果方面,抗菌剂的选择及添加量会影响牙科树脂材料的抗菌性能及机械性能;抗菌剂的口内长期抗菌效果有待验证;抗菌剂或其他环境因素会导致细菌产生耐药性甚至产生休眠状态的持留菌。近年来,研究学者致力于通过抗菌剂的改性来增强抗菌效果。除此之外,通过载体缓释抗菌剂也是主要的研究方向。本文对牙科树脂材料抗菌性能的研究进展进行综述。

关键词: 牙体缺损, 充填材料, 牙科树脂, 聚合收缩, 微渗漏, 继发龋, 抗菌剂, 载体, 缓释, 改性

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