Journal of Prevention and Treatment for Stomatological Diseases ›› 2017, Vol. 25 ›› Issue (1): 13-20.doi: 10.12016/j.issn.2096-1456.2017.01.003

• Special Articles • Previous Articles     Next Articles

A 50 years' single-center analysis of epidemiologic characteristics of oral cancer in Guangdong Province

Ji ZHANG1,2,Zhong-yuan YANG1,2,Xing ZHANG1,2,Shu-wei CHEN1,2,Fan GAO1,2,Xi-di WANG1,2,Ming SONG1,2()   

  1. 1. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, Guangzhou 510060, China
    2. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
  • Received:2016-07-20 Revised:2016-09-01 Online:2017-01-20 Published:2017-01-20
  • Contact: Ming SONG E-mail:songming@sysucc.org.cn

Abstract:

Objective To study the epidemiological characteristics of oral cancer and the pattern of the onset of oral cancer, in order to provide references for preventing and monitoring the development of oral cancer. Methods The information of 4 097 oral cancer patients who came from Guangdong province treated in the Sun Yat-Sen University Cancer center from 1960 to 2013 was retrospectively analyzed. SPSS 21.0 was used for the statistical analyses.Results The male-to-female ratio among oral cancer patients was approximately 2:1 and this ratio decreased over time. Oral cancer mostly occurred in patients between 45 to 64 years, and the percentage of elderly patients gradually increased over time. The most common location was the tongue especially lateral tongue. The pathological type of oral cancer was mainly squamous cell carcinoma. The percentage of O blood type in oral cancer patients was significantly lower than that in the normal population. The male-to-female ratio in the Chaoshan area was higher than that in the Guangfu area and the Hakka area, whereas the age of disease onset in the Guangfu area was higher than that in the Hakka and Chaoshan areas. The male-to-female ratio was lower and the age of disease onset was higher in the Pearl River Delta region than in the non-Pearl River Delta region.Conclusion During the process of screening for oral cancer, more attention should be paid to the middle-aged and elderly, males, and non-O blood type individuals. In addition, propaganda should be strengthened to encourage residents to change bad living habits.

Key words: Oral cancer, Epidemiology, Guangdong Province, Tongue cancer, Squamous cell carcinoma

CLC Number: 

  • R739.8

Table 1

Hospital admission characteristics of 4 097 oral cancer patients by sex from 1960 to 2013 n"

年份 合计 男女比
1960—1973 293 139 432 2.108
1974—1983 344 156 500 2.205
1984—1993 549 254 803 2.161
1994—2003 635 324 959 1.960
2004—2013 908 495 1 403 1.834
合计 2 729 1 368 4 097 1.995

Table 2

Hospital admission characteristics of 4 097 oral cancer patients by age at admission from 1960 to 2013 n"

入院年份 例数 年龄范围(岁) 中位数(岁) x?±s(岁) 0~24 岁 25~34岁 35~44岁 45~54 岁 55~64 岁 65~74 岁 75~岁
1960~ 432 4~82 49.5 49.1 ± 13.2 17 36 110 103 114 48 4
1974~ 500 13~82 50.5 50.4 ± 12.0 10 44 83 171 131 54 7
1984~ 803 3~83 54 52.0 ± 12.8 22 55 145 197 250 119 15
1994~ 959 3~97 55 53.6 ± 13.5 16 68 157 236 270 162 50
2004~2013 1 403 7~90 55 54.0 ± 13.3 31 84 216 349 413 239 71
合计 4 097 3~97 53 52.6 ± 13.2 96 287 711 1 056 1 178 622 147

Table 3

Initial position characteristics of 4 097 oral cancer patients from 1960 to 2013"

部位 例数 百分比(%)
舌体 2 230 54.4
口底 305 7.4
颊黏膜 367 9.0
牙龈 534 13.0
磨牙后区 18 0.4
硬腭 381 9.3
187 4.6
不详 75 1.8
合计 4 097 100.0

Table 4

Initial position characteristics of tongue cancer patients"

部位 例数 百分比(%)
舌侧缘 1 733 77.0
舌腹 296 13.3
舌背 82 3.7
舌尖 29 1.3
不详 90 4.0
合计 2 230 100.0

Table 5

Pathological characteristics of 4 097 oral cancer patients"

口腔癌病理类型 例数 百分比(%)
鳞癌 3 642 88.9
腺样囊性癌 119 2.9
粘液表皮样癌 77 1.9
恶性黑色素瘤 48 1.2
腺癌 32 0.8
基底细胞癌 28 0.7
恶性混合瘤 25 0.6
肉瘤 22 0.5
肌上皮癌 4 0.1
其他 100 2.4
合计 4 097 100.0

Table 6

Blood type characteristics of 4 097 oral cancer patients"

血型 频率 百分比(%)
A 1 021 24.9
B 1 039 25.4
AB 253 6.2
O 1 519 37.1
不详 265 6.5
合计 4 097 100.0

Table 7

Residential characteristics of 4 097 oral cancer patients by sex and age at admission"

地区 男女比 0~24岁 25~34岁 35~44岁 45~54岁 55~64岁 65~74岁 75岁~
广府 1 602 868 1.85 46 152 402 612 740 421 97
客家 315 173 1.82 16 33 95 142 129 58 15
潮汕 340 141 2.41 12 42 95 134 133 50 15

Table 8

Sex ratios and age composition of oral cancer in different economic level area n"

地区 男女比 0~24岁 25~34岁 35~44岁 45~54岁 55~64岁 65~74岁 75岁~
珠三角 1 617 862 1.88 41 145 394 627 738 433 101
非珠三角 736 336 2.19 33 92 213 279 295 130 30
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